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Isotopic labelings for mechanistic studies
The intricate mechanisms in the biosynthesis of terpenes belong to the most challenging problems in natural product chemistry. Methods to address these problems include the structure-based site-directed mutagenesis of terpene synthases, computational approaches, and isotopic labeling experiments. The latter approach has a long tradition in biosynthesisHouchao, Xu, Jeroen S, Dickschat
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Mapping isotopically labeled alanine
Science, 2019Electron Microscopy Electron microscopy of organic materials must avoid the destructive effects of electron beam impact. One approach is to measure vibrational spectra with electron energy-loss spectroscopy in a mode where the electron beam grazes the sample and couples to it through evanescent modes. Hachtel et al. used such methods to probe carbon-12–
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Radiopharmaceuticals labelled with bromine isotopes
International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes, 1986B, Maziere, C, Loc'h
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Isotopic labelling of proanthocyanidins
1997International ...
Deprez, S. +3 more
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A lithium-isotope perspective on the evolution of carbon and silicon cycles
Nature, 2021Boriana Kalderon-Asael +2 more
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Stable isotope probing — linking microbial identity to function
Nature Reviews Microbiology, 2005Marc G Dumont
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Ruthenium isotope vestige of Earth’s pre-late-veneer mantle preserved in Archaean rocks
Nature, 2020Mario Fischer-Gödde +2 more
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