Results 61 to 70 of about 100,704 (351)

Cell cycle length, cell size, and proliferation rate in hydra stem cells [PDF]

open access: yes, 1990
We have analyzed the cell cycle parameters of interstitial cells in Hydra oligactis. Three subpopulations of cells with short, medium, and long cell cycles were identified. Short-cycle cells are stem cells; medium-cycle cells are precursors to nematocyte
Bode   +34 more
core   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Revealing nascent proteomics in signaling pathways and cell differentiation. [PDF]

open access: yes, 2018
Regulation of gene expression at the level of protein synthesis is a crucial element in driving how the genetic landscape is expressed. However, we are still limited in technologies that can quantitatively capture the immediate proteomic changes that ...
Burlingame, Alma L   +8 more
core   +1 more source

Isotope Labeling in Mammalian Cells [PDF]

open access: yes, 2011
Isotope labeling of proteins represents an important and often required tool for the application of nuclear magnetic resonance (NMR) spectroscopy to investigate the structure and dynamics of proteins. Mammalian expression systems have conventionally been considered to be too weak and inefficient for protein expression.
Arpana, Dutta   +3 more
openaire   +2 more sources

Atomic Size Misfit for Electrocatalytic Small Molecule Activation

open access: yesAdvanced Functional Materials, EarlyView.
This review explores the application and mechanisms of atomic size misfit in catalysis for small molecule activation, focusing on how structural defects and electronic properties can effectively lower the energy barriers of chemical bonds in molecules like H2O, CO2, and N2.
Ping Hong   +3 more
wiley   +1 more source

Molecular elucidating of an unusual growth mechanism for polycyclic aromatic hydrocarbons in confined space

open access: yesNature Communications, 2020
Coke-induced catalyst deactivation draws increasing concerns in industrially catalytic processes. Here the authors provide a strategy integrating advanced mass spectroscopy and isotope labeling to uncover a cage-passing molecular route of coking species ...
Nan Wang   +11 more
doaj   +1 more source

Plasmodium falciparum ligand binding to erythrocytes induce alterations in deformability essential for invasion [PDF]

open access: yes, 2017
The most lethal form of malaria in humans is caused by Plasmodium falciparum. These parasites invade erythrocytes, a complex process involving multiple ligand-receptor interactions.
Cowman, Alan   +12 more
core   +2 more sources

Copper‐based Materials for Photo and Electrocatalytic Process: Advancing Renewable Energy and Environmental Applications

open access: yesAdvanced Functional Materials, EarlyView.
Cu‐based catalysts as a cornerstone in advancing sustainable energy technologies are fully reviewed in this manuscript, highlighting their potential in photo‐ and electrocatalysis. It includes metallic copper, copper oxides, copper sulfides, copper halide perovskites, copper‐based metal–organic frameworks (MOFs), and covalent organic frameworks (COFs),
Jéssica C. de Almeida   +16 more
wiley   +1 more source

Using 14C-acetate Pulse-chase Labeling to Study Fatty Acid and Glycerolipid Metabolism in Plant Leaves

open access: yesBio-Protocol, 2021
Lipids metabolism is comprised of networks of reactions occurred in different subcellular compartments. Isotopic labeling is a good way to track the transformations and movements of metabolites without perturbing overall cellular metabolism. Fatty acids,
Linhui Yu   +3 more
doaj   +1 more source

Binding to medium and long chain fatty acyls is a common property of HEAT and ARM repeat modules. [PDF]

open access: yes, 2019
Covalent post-translational modification (PTM) of proteins with acyl groups of various carbon chain-lengths regulates diverse biological processes ranging from chromatin dynamics to subcellular localization.
Chua, Katrin F   +7 more
core   +1 more source

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