Results 141 to 150 of about 154,472 (297)

Beyond Extracellular Vesicle (EV) Hype: Practical Solutions and Remaining Hurdles in EV Research, Manufacturing, and Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy, Zoe L. Chau, Sheng‐You Chen, Nanami Fujisawa, John J. Hill, Barnett M. Hsu, Joanne K. Liu, Karol W. Mai, James J. Lai   +8 more
wiley   +1 more source

Isotope ratio mass spectrometry and spectroscopic techniques for microplastics characterization. [PDF]

Talanta, 2021
Birch QT, Potter PM, Pinto PX, Dionysiou DD, Al-Abed SR.   +4 more
europepmc   +1 more source

Detachment‐Induced FAK‐STAT3‐NNMT Inhibits CTCs Anoikis to Promote Breast Cancer Metastasis by Enhancing Fatty Acid Oxidation

Advanced Science, EarlyView.
The FAK‐STAT3‐NNMT axis drives anoikis resistance in circulating tumor cells by reprogramming fatty acid oxidation. Targeting this metabolic vulnerability suppresses metastasis, untangling a key mechanism of breast cancer progression and revealing NNMT as a promising therapeutic target.
Qingchao Tong, Yilei Ma, Yuzhen Gao, Lin Zhou, Luping Lou, Qiang Fang, Sining Fang, Ru Zhao, Jin Zeng, Jun Yang, Guoli Li, Xinyou Xie, Yanzhong Wang, Jun Zhang   +13 more
wiley   +1 more source

Determining sugar and molasses origin by non‐exchangeable hydrogen stable isotope of ethanol and carbon isotope ratio mass spectrometry

Food Frontiers
This study explores the differentiation of sugar and molasses produced from sugar beet and cane, which are susceptible to fraudulent labeling due to differing production costs.
Macarena Rojas‐Rioseco, Hafiz Imran Fakhar, Ivan Smajlovic, Margarita Smajlovic, Stevan Grkavac, Mecit Halil Oztop, Muhammad Qasim Hayat, Rosario del P. Castillo   +7 more
doaj   +1 more source

Results of an Interlaboratory Comparison of a Liquid Chromatography-Isotope Ratio Mass Spectrometry Method for the Determination of 13C/12C Ratios of Saccharides in Honey. [PDF]

J AOAC Int, 2021
Aries E, De Rudder O, Kaklamanos G, Maquet A, Ulberth F.   +4 more
europepmc   +1 more source

Photonuclear Population of 229m,gTh in Th‐Doped Crystals Toward Nuclear Clock Development

Advanced Science, EarlyView.
This study demonstrates a novel photonuclear approach for producing the nuclear clock isomer 229mTh in thorium‐doped crystals, overcoming current supply limitations. Through cross‐section calculations and Monte Carlo simulations, we identify optimal crystal materials and irradiation conditions, achieving high signal‐to‐noise ratios.
Hao‐Yang Lan, Di Wu, Mei‐Zhi Wang, Zhong‐Yi Chen, Jian‐Feng Lv, Yu‐Hui Xia, Zhe‐Nan Wang, Wen Luo, Xin‐Lu Xu, Xue‐Qing Yan   +9 more
wiley   +1 more source

Application of gas chromatography-stable isotope mass spectrometry to determine the oxygen isotope ratio of water in concentrated fruit juice

Journal of Agriculture and Food Research
In this study, we developed a method to determine the authenticity of concentrated fruit juice using the δ18O ratio of water. We utilized the gas chromatography-isotope ratio mass spectrometry (GC-IRMS) technique along with the offline isotope exchange ...
Yulong Huang, Daobing Wang, Qiding Zhong, Di Feng, Hongmei An, Hongwei Yue, Zhuying Wu, Luoqi Zhang, Xuewu Guo, Shuojie Wang   +9 more
doaj   +1 more source

Authenticity Assessment of (E)-Cinnamic Acid, Vanillin, and Benzoic Acid from Sumatra Benzoin Balsam by Gas Chromatography Combustion/Pyrolysis Isotope Ratio Mass Spectrometry. [PDF]

Int J Anal Chem, 2022
Mao D, Hong L, Fu L, Li Z, Chen J, Zhang C, Wu Y, Xiong W, Wang J.   +8 more
europepmc   +1 more source

Erasable FAP Targeted Spray‐On Probe for Fluorescence‐Guided Surgery

Advanced Science, EarlyView.
We present the first erasable spray‐on probe for fluorescence‐guided surgery. Following topical delivery, FAP‐FLASH550 targets fibroblast activation protein–expressing stromal cells, delineating tumor margins with high tumor‐to‐background ratios. A 365 nm UV light pulse rapidly erases fluorescent signals through triazene photodegradation and subsequent
Zachary Rabinowitz, Riley J. Deutsch‐Williams, Ralph Weissleder   +2 more
wiley   +1 more source

Gas Chromatography Combustion Isotope Ratio Mass Spectrometry to Detect Differences in Four Compartments of Simmental Cows Fed on C3 and C4 Diets. [PDF]

Molecules, 2022
Pianezze S, Corazzin M, Bontempo L, Sepulcri A, Saccà E, Perini M, Piasentier E.   +6 more
europepmc   +1 more source