Results 121 to 130 of about 224,948 (306)
Advanced Science, EarlyView.Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang +12 more
wiley +1 more source
Stable isotopes and sedimentology of core GeoB1035
, 2001 Stable isotopes and sedimentology of core ...
Gerold Wefer (6958886) +5 more
core +1 more source
Advanced Science, EarlyView.We demonstrate that the inverse relationship between viscosity and conductivity in structured electrolytes can be circumvented by leveraging their hydrogen bonding networks for Grotthuss proton transport. Using a mixture of imidazole and levulinic acid, we show that the existence of extended hydrogen‐bonded chains that can rapidly reorient result in ...
Benworth B. Hansen +15 more
wiley +1 more source
Stable isotopes and sedimentology of core GeoB1034
, 2009 Stable isotopes and sedimentology of core ...
Gerold Wefer (6958886) +5 more
core +1 more source
A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior
Advanced Science, EarlyView.Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li +12 more
wiley +1 more source
Nitrogen Isotopes in the Global Ocean [PDF]
, 2013 Nitrogen is an essential nutrient for life. Its low abundance throughout much of the sunlit surface ocean limits the growth of primary producers that form the base of ocean ecosystems.
Somes, Christopher J. +1 more
core
Aspirin‐Derived Salicyl‐CoA Drives Histone Lysine Salicylation Regulated by CBP and SIRT2
Advanced Science, EarlyView.Aspirin‐derived salicyl‐CoA serves as a previously unrecognized acyl donor for protein lysine salicylation. This study identifies histone lysine salicylation as a reversible epigenetic modification regulated by CBP and SIRT2, expanding the biochemical actions of aspirin beyond its canonical acetylation‐dependent mechanisms and providing a new framework
Facai Zhang +15 more
wiley +1 more source
Stable isotopes of sediment core PS1769-1
, 2002 Stable isotopes of sediment core PS2085-
Hans-Stefan Niebler (6976133) +1 more
core +1 more source
Advanced Science, EarlyView.Polystyrene nanoplastics exacerbate high‐fat diet‐induced metabolic dysfunction in an age‐dependent manner. Juvenile mice exhibit greater susceptibility, characterized by circadian disruption, impaired mitochondrial function, reduced energy metabolism, and enhanced hepatic lipid accumulation.
Peihao Xu +10 more
wiley +1 more source
Final-state rescattering mechanism of charmed baryon decays
Journal of High Energy PhysicsThe dynamical studies on the non-leptonic weak decays of charmed baryons are always challenging, due to the large non-perturbative contributions at the charm scale. In this work, we develop the final-state rescattering mechanism to study the two-body non-
Cai-Ping Jia +3 more
doaj +1 more source