Results 191 to 200 of about 224,948 (306)

Tip60‐Mediated USP22 Lactylation Drives Glutamine Metabolic Reprogramming via SLC25A5 in TNBC

Advanced Science, EarlyView.
Tip60‐mediated USP22 K134 lactylation, stabilizing SLC25A5 to enhance glutamine metabolism and α‐KG secretion. The secreted α‐KG drives GPR91‐dependent M2 macrophage polarization, promoting triple‐negative breast cancer progression. Targeting this axis synergizes with CB‐839, offering a promising therapeutic strategy for TNBC.
Fang Zhen, Hongyi Wang, Ningzhi Zhang, Le Wang, Huiyuan Tian, Luxi Kang, Zhanpeng Liu, Jing Hu   +7 more
wiley   +1 more source

Bioconversion of β-carotene to vitamin A across life stages using stable isotope methodologies: a protocol for the systematic review. [PDF]

Syst Rev
Frane RD, Lat HT, Semilla JJL, Diaz JMS, Zumaraga MPP.   +4 more
europepmc   +1 more source

Lactate Drives Pathological Browning of White Adipose Tissue to Aggravate Sepsis‐Associated Metabolic Disorders in a GPR81‐Dependent Manner

Advanced Science, EarlyView.
Sepsis‐triggered lactate accumulation induces pathological white adipose tissue browning. Lactate activates adipocyte GPR81 to sequentially upregulate CTRP6‐p38 signalling and UCP1 expression. This cascade exacerbates sepsis‐associated metabolic disorders.
Chunliang Zheng, Xiaohua Li, Shuo Li, Chungen Xing, Chun Cao   +4 more
wiley   +1 more source

A Multi-Isotope Approach (δ²H, δ¹⁸O, δ¹³C, δ¹⁵N) for Discriminating Raspberry Production Systems and Assessing Agroecosystem Functioning. [PDF]

Molecules
Ionete RE, Costinel D, Simionescu AM, Miricioiu MG, Pruteanu A, Istrate AI, Botoran OR.   +6 more
europepmc   +1 more source

Pre‐Refinement Prediction of Dopant Site Occupancy in M‐Type Hexaferrites via Hierarchical and Uncertainty‐Aware Machine‐Learning

Advanced Science, EarlyView.
Refined data are extracted from CIF files to construct a hierarchical machine‐learning framework integrating sublattice classification, Fe‐site occupancy prediction, and reliability assessment. External validation yields 96% accuracy for sublattice classification and a macro mean absolute error of 0.0584 for Fe‐site prediction.
Dan Liu, Jianyu Ren, Ruoshui Liu, Yinong Yin, Jianfeng Xi, Xin Ming, Jiazheng Hao, Tongyun Zhao, Fengxia Hu, Baogen Shen   +9 more
wiley   +1 more source

Are ⁶¹Cu, ⁶⁴Cu, and ⁶⁷Cu Really Happening? [PDF]

J Nucl Med
Zimmermann R.
europepmc   +1 more source

Overcoming the *H‐NOx Coupling Bottleneck via Palladium‐Enabled Relay Catalysis on CuCo2O4 Toward Ampere‐Level Nitrate‐to‐Ammonia

Advanced Science, EarlyView.
Pd‐doped hollow spiny CuCo2O4 microspheres deliver ampere‐level electrocatalytic nitrate to ammonia. Cu and Co sites undergo relay catalysis for sequential nitrate reduction, while Pd accelerates water dissociation to supply abundant active hydrogen (*H).
Yuhuan Cui, Yingying Xu, Jingyao Guo, Yao Liu, Yuxuan Li, Zixuan Feng, Yitong Zhou, Yongjun Gao, Zhili Wang   +8 more
wiley   +1 more source

Cloud point extraction and preconcentration of gold in geological matrices prior to flame atomic absorption determination

Open Chemistry, 2010
El-Naggar Wifky, Lasheen Taysseer, Nouh El-Said, Ghonaim Ahmed   +3 more
doaj   +1 more source

New insights into the Trans-Saharan gold trade in the Islamic Middle Ages revealed by multi-isotopic (Pb-Fe-Cu) and elemental characterization of Fatimid gold coins. [PDF]

PLoS One
de Palaminy L, Baron S, Poitrasson F, Kool R, Blet-Lemarquand M, Fauvelle FX.   +5 more
europepmc   +1 more source

Electrocatalytic Urea Synthesis From CO2 and N2/NO3−: Bridging Catalyst Activity, C–N Coupling Kinetics, and Industrial Applicability

Advanced Science, EarlyView.
This review compares NO3− + CO2 and N2 + CO2 electrocatalytic urea synthesis in feedstock properties, catalyst design, C–N coupling mechanisms, performance optimization, and engineering applicability. The two systems correspond to a near‐term deployable route and a long‐term green synthesis goal, respectively.
Fulin Dong, Ruihan Zhang, Huiyu Lou, Tianshi Gao, Guangjin Zhang, Menglei Yuan   +5 more
wiley   +1 more source