Results 231 to 240 of about 792,425 (354)
Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu+9 more
wiley +1 more source
Heavy boron isotopes in intraplate basalts reveal recycled carbonate in the mantle. [PDF]
Xu R+11 more
europepmc +1 more source
The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen+6 more
wiley +1 more source
Mechanism of lateral cell-wall expansion at a constant diameter in Bacillus subtilis. [PDF]
Liang Y+6 more
europepmc +1 more source
Acidosis Forces Fatty Acid Uptake and Metabolism in Cancer Cells Regardless of Genotype
This study demonstrates that biological acidosis, commonly observed in tumors and ischemic conditions, actively promotes the protonation of fatty acids, thereby facilitating the uptake of their neutral forms. Consequently, the preference for lipid metabolism in acid‐exposed cells does not arise from genetic reprogramming that prioritizes lipids as the ...
Sébastien Ibanez+20 more
wiley +1 more source
Passive degassing of lithospheric volatiles recorded in shallow young groundwater. [PDF]
Tyne RL+8 more
europepmc +1 more source
In this work, an electrochemical strategy employing hydroperoxyl radicals and a molybdenum‐based catalyst (Mo─N─O) enables selective double‐bond oxidation in cinnamaldehyde, preserving aldehyde integrity. Under mild, energy‐efficient conditions (−200 mA), this approach converts cinnamaldehyde to benzaldehyde with complete conversion (100%) and >99 ...
Zhirong Li+12 more
wiley +1 more source