Results 241 to 250 of about 653,557 (305)

Neodymium and lead isotopes from manganese crust S1601-13 (ROM16)

open access: green, 2003
Martin Frank   +5 more
openalex   +1 more source

Alternative Pathway for Methyl Supply through the Coupling of SHMT1 and PEMT to Maintain Astrocytic Homeostasis in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
In Parkinson's disease, SHMT1 downregulation disrupts its interaction with PEMT in astrocytes, reducing SAM levels. This leads to H3K4me1 hypomethylation and decreased Slc1a2/Glul expression, ultimately exacerbating neuroexcitotoxicity and dopaminergic neuron loss.
Yue‐Han Chen   +17 more
wiley   +1 more source

Corrigendum to "Enhancing the reconstruction of the Gabasa Neandertal's diet using Ca and Sr stable isotopes" [J. Hum. Evol. 207 (2025) 103747].

open access: yesJ Hum Evol
Dodat PJ   +7 more
europepmc   +1 more source

Stable Isotope and Elemental Characteristics for Origin Identification of Rice from China and Thailand. [PDF]

open access: yesPlants (Basel)
Xing X   +7 more
europepmc   +1 more source

(Table 3) Abundance and isotope composition of hydrogen and carbon extracted during step-heating technique from samples of ODP/IODP Hole 1256D

open access: green, 2002
С. Н. Шилобреева   +4 more
openalex   +1 more source

Spatially Resolved Multiomics Reveals Metabolic Remodeling and Autophagy Activation in Adamantinomatous Craniopharyngiomas

open access: yesAdvanced Science, EarlyView.
Multiomics integration analysis reveals the “cystic fluid–tumor cell” metabolic coupling that mediates active choline/ethanolamine uptake of tumor cells from cystic fluid and PC/PE synthesis pathways reprogramming that mediating autophagy pathway activation within ACP. ABSTRACT Adamantinomatous craniopharyngioma (ACP), a benign yet highly recurrent and
Dongting Chen   +9 more
wiley   +1 more source

Structure‐Guided Engineering of a Promiscuous O‐Methyltransferase for a SAM Regeneration Biocatalysis Platform of Methylated Pharmaceuticals

open access: yesAdvanced Science, EarlyView.
A substrate promiscuous and regioselective O‐methyltransferase, SmOMT, is functionally and structurally characterized. A double mutant, SmOMTE152A/I306A, exhibited enhanced catalytic activity. By coupling this mutant with a mutant halide methyltransferase, AtHMTV140T, for SAM regeneration, a superior artificial fusion enzyme, AtHMTV140T‐L95‐SmOMTE152A ...
Xiran Xiong   +11 more
wiley   +1 more source

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