Results 41 to 50 of about 653,557 (305)

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Recyclable Robust Plastic Scintillation Resin Achieving the Exceptional Separation and Detection of Technetium‐99

Advanced Science
Rapid detection and absorption of 99TcO4⁻ contamination in the environment are critical due to its high radioactivity, long half‐life, and significant environmental mobility.
Tonghuan Liu, Yichen Hu, Junqiang Yang, Kesheng Hu, Bei Qi, Yun Zhou, Juan Tong, Man Wang, Liang Huang, Keliang Shi, Xiaolin Hou   +10 more
doaj   +1 more source

Simulation and Comparative Study of Interaction Between Ray and Medium in Borehole Based on FLUKA Software

Cejing jishu
In nuclear logging, Monte Carlo simulation method is widely employed across various stages from instrument development and design to data interpretation.
LIU Juntao, LI Wenxin, MARINA R. ABDELNOUR, TIAN Heng, WANG Yiwei, GAO Yuan, LIU Zhiyi   +6 more
doaj   +1 more source

Current Status and Recent Achievements of the Sterile Insect Technique Program Against Dengue Vector, Aedes aegypti, in Indonesia

Atom Indonesia, 2019
Given the facts that Indonesia has suitable environment condition to survival, reproduction and development of the principal mosquito vector for dengue virus, Aedes aegypti, the transmission of dengue virus does routinely occur every year.
B. Ernawan, H.I. Sasmita, M. Sadar, I. Sugoro   +3 more
doaj   +1 more source

Core–shell structured gold nanoparticles as carrier for 166Dy/166Ho in vivo generator

EJNMMI Radiopharmacy and Chemistry, 2022
Background Radionuclide therapy (RNT) has become a very important treatment modality for cancer nowadays. Comparing with other cancer treatment options, sufficient efficacy could be achieved in RNT with lower toxicity.
Runze Wang, Bernard Ponsard, Hubert Wolterbeek, Antonia Denkova   +3 more
doaj   +1 more source

Discovery of the Isotopes with 11 <= Z <= 19

, 2011
A total of 194 isotopes with 11 $\le$ Z $\le$ 19 have been identified to date. The discovery of these isotopes which includes the observation of unbound nuclei, is discussed.
Ajzenberg-Selove, Alvarez, Amaldi, Andersen, Artukh, Aston, Aston, Aston, Aston, Aston, Aston, Aston, Aston, Audi, Auger, Barton, Baumann, Benenson, Benenson, Benenson, Berg, Bethe, Birge, Boley, Bradner, Brosi, Butler, Cable, Cable, Cerny, Churchill, Cohen, Corson, Creutz, Curie, Curie, Dempster, Dempster, Détraz, Eckardt, Ellis, Fahlenbrach, Fermi, Frisch, Frisch, Ginepro, Glass, Goriely, Grahame, Grimm, Grévy, Guillemaud-Mueller, Guillemaud-Mueller, Hagberg, Hansen, Hardy, Hardy, Haslam, Hevesy, Hoag, Hollander, Huber, Huber, Huber, Huck, Hurst, Jelley, Joliot, Kashy, Katcoff, Kennedy, King, Klapisch, Klapisch, Klapisch, Kuerti, Kuroyanagi, Langevin, Langevin, Langevin, Larson, Lederer, Lewitowicz, Lindner, Lindner, Livingood, Lukyanov, M. Thoennessen, MacFarlane, Mantica, Marinov, McPherson, Meye, Miller, Morinaga, Morinaga, Morris, Mukha, Mulliken, Nethaway, Nier, Nier, Notani, Nurmia, Overstreet, Pollard, Pool, Reeder, Robertson, Robinson, Robinson, Robinson, Saint-Laurent, Sakurai, Sakurai, Seaborg, Seaborg, Sheline, Sheline, Snell, Strominger, Stähelin, Sun, Symons, Tarasov, Tarasov, Thoennessen, Turkevich, Tyren, Van Voorhis, Walke, Weimer, Westfall, White, White, Yaffe, Zeeman, Zerguerras, Zünti, Äystö   +139 more
core   +1 more source

CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez, Corinne Pettigrew, Yuxin Zhu, Claire Anderson, Guray Erus, Christos Davatzikos, Michael Miller, Abhay Moghekar, Sungtaek Oh, Chan‐Hyun Na, Marilyn Albert, Paul Worley, Anja Soldan   +12 more
wiley   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Effect of Gamma Irradiation on Mechanical and Thermal Properties of Fish Gelatin Film Isolated from Lates Calcarifer Scales

Indonesian Journal of Chemistry, 2013
The objective of this research was to investigate the effect of gamma irradiation on mechanical and thermal properties of fish gelatin films prepared from scales of Lates calcarifer. The films were irradiated by gamma rays at varied doses (0-50 kGy). The
Dian Pribadi Perkasa, Erizal Erizal, Darmawan Darmawan, Akhmad Rasyid   +3 more
doaj   +1 more source