Results 101 to 110 of about 173,935 (289)

Carbon Isotope Ratios of Various Fruits

open access: yesJournal of AOAC INTERNATIONAL, 1986
Abstract Carbon stable isotope ratio analysis (SIRA) has been applied to detect adulteration of apple, orange, honey, and other products with cane or corn sugars. We analyzed numerous other fruits to determine the applicability of carbon SIRA to detecting adulteration in these fruits as well.
Harold W Krueger   +2 more
openaire   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

open access: yesAdvanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong   +5 more
wiley   +1 more source

Significant carbon isotopic fractionation during early formation of biological soil crusts with indications for dryland carbon cycling

open access: yesiScience
Summary: Clarifying the accumulation and decomposition of soil organic carbon (SOC) is crucial for comprehending carbon cycling in terrestrial ecosystems.
Li-Xuan Zhang   +5 more
doaj   +1 more source

Cryo‐EM Structure Guided Engineering of Botulinum Neurotoxin A With Advanced Receptor Binding Affinity and Therapeutical Benefits

open access: yesAdvanced Science, EarlyView.
The butterfly unfolded wing in an open form structure of botulinum neurotoxin type A (BoNT/A) at physiological‐state was confirmed at 2.85 Å resolution by cryo‐electron microscopy (cryo‐EM). Structure‐guided protein engineering significantly enhanced the receptor‐binding affinity, therapeutic efficacy, and safety of the engineered toxin variants ...
Wenrui Wang   +16 more
wiley   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

open access: yesAdvanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao   +14 more
wiley   +1 more source

Zinc Isotope Ratios as Indicators of Diet and Trophic Level in Arctic Marine Mammals.

open access: yesPLoS ONE, 2016
Carbon and nitrogen stable isotope ratios of bone collagen are an established method for dietary reconstruction, but this method is limited by the protein preservation.
Klervia Jaouen   +2 more
doaj   +1 more source

Study on the Optimal Reaction Temperature and Sampling Weight for Measurement of Carbon and Nitrogen Isotope Ratio by Elemental Analyzer-Isotope Ratio Mass Spectrometer

open access: yesYankuang ceshi, 2018
Carbon and nitrogen isotopes are essential tools to study paleoclimate, palaeoenvironment, and ecosystem. At present, carbon and nitrogen isotopes are commonly determined by Elemental Analyzer-Isotope Ratio Mass Spectrometer (EA-IRMS).
XU Li   +4 more
doaj   +1 more source

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