Results 241 to 250 of about 33,246 (294)

Isotretinoin

Reactions weekly, 2020
Isotretinoin is chemically named as: (2Z, 4E, 6E, 8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenoic acid. It is an orally active retinoic acid derivative for the treatment of severe refractory nodulocystic acne. It acts primarily by reducing sebaceous gland size and sebum production, and as a result alters skin surface lipid ...
Nasr Y, Khalil, Ibrahim A, Darwish, Abdulmohsen A, Al-Qahtani   +2 more
openaire   +3 more sources

Analysis of the use of isotretinoin as an adjuvant in rhinoplasty

International Journal of Dermatology, 2023
Isotretinoin has been used in the treatment of acne for decades through the reduction of sebaceous secretion. There are reports in the literature that isotretinoin may be associated with decreased skin thickness, especially in patients with thick nasal ...
C. S. C. Silveira, L. Azulay‐Abulafia, E. Barcaui, Matheus M M Silva, Ana Claudia W Roxo   +4 more
semanticscholar   +1 more source

Isotretinoin Laboratory Monitoring in Acne Treatment: A Delphi Consensus Study.

JAMA dermatology, 2022
Importance Although isotretinoin may rarely be associated with laboratory abnormalities such as hypertriglyceridemia, the optimal approach to laboratory monitoring is uncertain, and there is wide variation in clinical practice. Objective To establish a
Eric Xia, Jane J. Han, A. Faletsky, H. Baldwin, K. Beleznay, V. Bettoli, B. Dréno, C. Goh, L. S. Stein Gold, H. Gollnick, M. I. Herane, Sewon Kang, L. Kircik, Julianne A Mann, A. Nast, H. Oon, Jo-Ann See, M. Tollefson, G. Webster, C. Zip, Jerry Tan, E. Tapper, D. Thiboutot, A. Zaenglein, J. Barbieri, A. Mostaghimi   +25 more
semanticscholar   +1 more source

Oral isotretinoin for acne: a complete overview

Expert Opinion on Drug Safety, 2022
Introduction Acne is one of the most common and widespread skin conditions, affecting the health as much as patients’ quality of life. A wide variety of treatments for acne, topical and systemics, could be prescribed, depending on its degree of severity.
A. Villani, F. Nastro, Francesca di Vico, G. Fabbrocini, M. C. Annunziata, L. Genco   +5 more
semanticscholar   +1 more source

Systemic isotretinoin has an impact on hemoglobin, ferritin, urea, ceruloplasmin, albumin, uric acid levels, and neutrophil to lymphocyte ratio in acne patients

Journal of Cosmetic Dermatology, 2022
Patients suffering from moderate‐to‐severe acne are commonly treated with systemin isotretinoin; however, a great controverse about its safety had been raised. The aim of the present study is to evaluate the effects of isotretinoin on hepatic, renal, and
M. Hareedy, K. Tawfik
semanticscholar   +1 more source

The use of isotretinoin for acne – an update on optimal dosing, surveillance, and adverse effects

Expert Review of Clinical Pharmacology, 2020
Introduction Acne is a chronic, inflammatory, and immune mediated disease of pilosebaceous unit, highly prevalent in adolescents. It involves face, trunk, and back; may leave scars and affect quality of life.
E. Bagatin, C. S. Costa
semanticscholar   +1 more source

Isotretinoin‐Induced Agranulocytosis

Pediatric Dermatology, 2007
Abstract:  Isotretinoin is used to treat a spectrum of dermatologic conditions. The present article reports the case of a 15‐year‐old female patient who exhibited agranulocytosis after the initiation of isotretinoin administration. Agranulocytosis is a rare but life‐threatening side effect of isotretinoin use, and clinicians must be aware of ...
Patiroglu, Türkan, Kose, Mehmet, Ozdemir, Mehmet Akif, FERAHBAS, Ayten, Koklu, Esad, Karakukcu, Musa   +5 more
openaire   +3 more sources