Results 271 to 280 of about 32,281 (298)

Isoxazole Strategy for the Synthesis of 2,2'-Bipyridine Ligands: Symmetrical and Unsymmetrical 6,6'-Binicotinates, 2,2'-Bipyridine-5-carboxylates, and Their Metal Complexes.

Journal of Organic Chemistry, 2019
An effective strategy was developed for the synthesis of new 2,2'-bipyridine ligands, symmetrical and unsymmetrical 6,6'-binicotinates, and 2,2'-bipyridine-5-carboxylates, from 4-propargylisoxazoles.
E. Galenko, M. Novikov, F. M. Shakirova, J. Shakirova, I. V. Kornyakov, Vladimir A Bodunov, A. Khlebnikov   +6 more
semanticscholar   +1 more source

A Review on Recent Synthetic Strategies and Biological Activities of Isoxazole

Journal of Heterocyclic Chemistry, 2022
C. Pandhurnekar, Himani C. Pandhurnekar, A. Mungole, S. Butoliya, Babita G. Yadao   +4 more
semanticscholar   +1 more source

Recent Updates in Curcumin Pyrazole and Isoxazole Derivatives: Synthesis and Biological Application

Chemistry and Biodiversity, 2019
Curcumin is an admired, plant‐derived compound that has been extensively investigated for diverse range of biological activities, but the use of this polyphenol is limited due to its instability.
Satyendra Mishra, Sejal Patel, Chandni G Halpani   +2 more
semanticscholar   +1 more source

Oxazole and isoxazole: From one-pot synthesis to medical applications

Tetrahedron, 2022
Ajay Thakur, M. Verma, R. Bharti, Renu Sharma   +3 more
semanticscholar   +1 more source

Claisen isoxazole synthesis

2009
Cyclization of β-keto esters with hydroxylamine to provide 3-hydroxy-isoxazoles (3-isoxazolols).
openaire   +2 more sources

Convenient route to benzo[1,2,3]selenadiazole–isoxazole hybrids and evaluation of their in vitro cytotoxicity

Chemické zvesti, 2022
Ali Oubella, Mourad Fawzi, Abdoullah Bimoussa, A. N’ait Ousidi, A. Auhmani, A. Riahi, A. Robert, L. El Firdoussi, H. Morjani, Moulay Youssef Ait Itto   +9 more
semanticscholar   +1 more source

Effect of isoxazole derivatives of tetrahydrofuran neolignans on intracellular amastigotes of Leishmania (Leishmania) amazonensis: A structure–activity relationship comparative study with triazole‐neolignan‐based compounds

Chemical Biology and Drug Design, 2019
Isoxazole analogues derived from the neolignans veraguensin, grandisin, and machilin G were previously synthesized with different substitution patterns through the bioisosterism strategy.
Amarith R. Neves, Ozildéia S. Trefzger, Natália V Barbosa, A. M. Honorato, Diego B. Carvalho, I. S. Moslaves, M. C. T. Kadri, Nídia C. Yoshida, M. Kato, C. Arruda, A. Baroni   +10 more
semanticscholar   +1 more source

Structure-Based Discovery and Optimization of Benzo[ d]isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer (CRPC).

Journal of Medicinal Chemistry, 2018
The bromodomain and extra-terminal (BET) family proteins have gained increasing interest as drug targets for treatment of castration-resistant prostate cancer (CRPC).
Maofeng Zhang, Yan Zhang, Minghu Song, Xiao-qian Xue, Junjian Wang, Chao Wang, Cheng Zhang, Chen-chang Li, Qiuping Xiang, Ling-jiao Zou, Xi-shan Wu, Chun-Lei Wu, B. Dong, W. Xue, Yu-lai Zhou, Hongwu Chen, Donghai Wu, Ke Ding, Yong Xu   +18 more
semanticscholar   +1 more source

Isoxazole derivatives as anticancer agent: A review on synthetic strategies, mechanism of action and SAR studies.

European journal of medicinal chemistry, 2021
G. Arya, K. Kaur, Vikas Jaitak
semanticscholar   +1 more source

Synthesis of New Isoxazole-, Pyridazine-, Pyrimidopyrazines and Their Anti-Inflammatory and Analgesic Activity.

Medicinal chemistry, 2018
BACKGROUND Isoxazoles, pyridazines, and pyrimidopyrazines have recently attracted attention due to their potent pharmacological activities. They exhibited anticancer, neuroprotective, analgesic and anti-inflammatory effects.
A. Abu‐Hashem, M. El‐Shazly
semanticscholar   +1 more source