Results 251 to 260 of about 8,819 (284)

A three-component cycloaddition of alkyl trifluorodiazoethane for the synthesis of trifluoromethylated isoxazolines

Chemistry of Heterocyclic Compounds, 2023
Jingwen Xu, Jiang Liu, Haibo Mei, V. Soloshonok, Jianlin Han   +4 more
semanticscholar   +1 more source

Isoxazolines and isoxazoles as factor Xa inhibitors

Bioorganic & Medicinal Chemistry Letters, 2000
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Ruth R. Wexler, Matthew R. Wright, Robert M. Knabb, Donald J. P. Pinto, Melissa J. Estrella, Pancras C. Wong, James Russell Pruitt, Lori L. Bostrom   +7 more
openaire   +4 more sources

Synthesis of Isoxazoline-Substituted Symmetrical Diketopiperazines

Synlett, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Marilyn M. Olmstead, Kyung Ho Park, Mark J. Kurth   +2 more
openaire   +3 more sources

Copper-Mediated Domino Cyclization/Trifluoromethylation of Propargylic N-Hydroxylamines: Synthesis of 4-Trifluoromethyl-4-isoxazolines.

Journal of Organic Chemistry, 2018
A Cu(OTf)2-mediated synthesis of trifluoromethylated 4-isoxazolines is described. In one step from readily available propargylic N-hydroxylamines, a domino 5-endo-dig cyclization, followed by trifluoromethylation, takes place to construct the 4 ...
Quan-Fu Wang, G. Tsui
semanticscholar   +1 more source

Synthesis, Antioxidant, and Antibacterial Activities of Two Novel Series of 3,5-Disubstituted Isoxazole Ether-Linked Isoxazolines and 3,5-Disubstituted Pyrazole Ether-Linked Isoxazolines Mediated by Chloramine-T

Russian journal of bioorganic chemistry, 2022
E. M. Saleh, S. Y. Kotian, A. M. Al Dawsari, I. Hassan, K. Husain, P. Abishad, K. Byrappa, R. Sharabi, K. Rai   +8 more
semanticscholar   +1 more source

Synthesis of 4-Isoxazolines via Visible-Light Photoredox-Catalyzed [3 + 2] Cycloaddition of Oxaziridines with Alkynes.

Organic Letters, 2017
A method for [3 + 2] cycloaddition of oxaziridines with alkynes to form 4-isoxazolines via visible-light photoredox catalysis is described. This method is a greener, atom-economical reaction that tolerates various functional groups and provides good to ...
Gwang Seok Jang, Junggeun Lee, J. Seo, S. Woo   +3 more
semanticscholar   +1 more source

P(NMe2)3-Mediated Reductive (1 + 4) Annulation Reaction of Isatins with Nitroalkenes: An Access to Spirooxindolyl Isoxazoline N-Oxides and Their Corresponding Isoxazolines.

Journal of Organic Chemistry, 2017
The reductive (1 + 4) annulation reaction of isatins and substituted nitroalkenes mediated by a trivalent phosphorus reagent has been realized for the first time, providing easy access to spirooxindolyl isoxazoline N-oxides in moderate to excellent ...
Yiyi Liu, Hengyuan Li, Xun Zhou, Zhengjie He   +3 more
semanticscholar   +1 more source

Access to Cyano-Containing Isoxazolines via Copper-Catalyzed Domino Cyclization/Cyanation of Alkenyl Oximes.

Journal of Organic Chemistry, 2017
A highly efficient copper-catalyzed cyclization/cyanation cascade of unactivated olefins bearing oximes is described. A variety of cyano-containing isoxazolines have been obtained in high yields with cheap Cu(NO3)2·3H2O as the catalyst and TMSCN as the ...
Fei Meng, Honglin Zhang, Kangkang Guo, Jiayue Dong, Ai-min Lu, Yingguang Zhu   +5 more
semanticscholar   +1 more source

Iron(III)-catalyzed selective N–O bond cleavage to prepare tetrasubstituted pyridines and 3,5-disubstituted isoxazolines from N-vinyl-α,β-unsaturated ketonitrones

, 2018
An iron(III)-catalyst controlled cyclization and selective N–O bond cleavage of N-vinyl-α,β-unsaturated nitrones has been achieved under mild conditions to access tetrasubstituted pyridines and 3,5-disubstituted isoxazolines in moderate to good yields ...
Chunhua Chen, Qing-Yan Wu, Cui Wei, Cui Liang, Gui-Fa Su, Dong‐Liang Mo   +5 more
semanticscholar   +1 more source

A three-component approach to isoxazolines and isoxazoles under metal-free conditions.

Organic and biomolecular chemistry, 2019
A 1,3-dipolar cycloaddition of 2-methylquinoline, tert-butyl nitrite (TBN) and alkynes or alkenes for the synthesis of biheteroaryls containing both isoxazoline/isoxazole and quinoline motifs has been developed.
Dahan Wang, Feng Zhang, Fuhong Xiao, G. Deng   +3 more
semanticscholar   +1 more source