Results 41 to 50 of about 56,415 (191)

Effector‐Mediated Spatial Reprogramming of Glycolate Oxidase Subverts Peroxisomal and Membrane‐Associated ROS Defences

Plant Biotechnology Journal, EarlyView.
ABSTRACT Oomycete pathogens secrete hundreds of RXLR effectors into plant cells to modulate host immunity by targeting diverse plant proteins. Here, we report that the Peronophythora litchii RXLR effector PlAvh133 acts as a virulence factor and targets the litchi glycolate oxidase (GLO) LcGLO1, a key enzyme in photorespiration, thereby suppressing ...
Junjian Situ, Zijing Zhang, Yi Shao, Jiaying Feng, Feiteng Zhong, Muran Xiong, Wen Li, Peng Li, Xiaofan Zhou, Guibing Hu, Jietang Zhao, Minhui Li, Pinggen Xi, Xinxiang Peng, Zide Jiang, Guanghui Kong   +15 more
wiley   +1 more source

Trypanosoma cruzi: inhibition of alpha-hydroxyacid dehydrogenase isozyme II by N-allyl and N-propyl oxamates and their effects on intact epimastigotes

Memorias do Instituto Oswaldo Cruz, 2004
N-allyl (NAOx) and N-propyl (NPOx) oxamates were designed as inhibitors of alpha-hydroxyacid dehydrogenase (HADH) isozyme II from Trypanosoma cruzi. The kinetic studies showed that NAOx and NPOx were competitive inhibitors of HADH-isozyme II (Ki = 72 µM,
Miguel A Chena, Silvia Elizondo-Jiménez, Lorena Rodríguez-Páez, Benjamín Nogueda-Torres, Isabel Baeza-Ramírez, Carlos Wong-Ramírez   +5 more
doaj   +1 more source

Antiplasmodial Activity and Pharmacokinetic Profiling of Cryptolepine and 2,7‐Dibromocryptolepine With a View to Informing the Design of Novel Antimalarial Cryptolepine Analogues

Drug Development Research, Volume 87, Issue 2, April 2026.
ABSTRACT The roots of the climbing shrub Cryptolepis sanguinolenta are traditionally used in West Africa for the treatment of malaria. The principal constituent, cryptolepine (1), has been shown to have antimalarial activity but there are concerns regarding its toxicity on account of its DNA‐intercalating property.
Elodie Chenu, James Duffy, Arnold Donkor Forkuo, Stephen Y. Gbedema, Seham Abdelall, Muhammad Wahajuddin, Huw S. Jones, Colin W. Wright   +7 more
wiley   +1 more source

An Electrophoretic Study of LDH-Isozyme Distribution in Developing Embryonic and Adult Tissues of the Toad Bufo arabicus

Sultan Qaboos University Journal for Science, 2009
Lactate (LDH) dehydrogenases were studied by electrophoresis to investigate the possibility of isozymic differences in different  stages and organs of B. arabicus embryos, tadpoles and adults.
Intisar Ambusaidi, Taher Ba-Omar, Saif Al-Bahri, Aisha Al-Shihi   +3 more
doaj   +1 more source

Dietary essential oils modulate post‐mortem oxidative damage in trout fillets exposed to slaughter stress during frozen storage

Journal of the Science of Food and Agriculture, Volume 106, Issue 6, Page 3686-3695, April 2026.
Abstract BACKGROUND Slaughter is a critical phase in aquaculture that can severely compromise both animal welfare and product quality. Stress responses triggered during this stage may accelerate post‐mortem biochemical degradation and promote oxidative damage in fish fillets. Essential oils, known for their antioxidant and anti‐inflammatory properties,
Lucía Méndez, Giulia Secci, Lorena Barros, Gabriel Dasilva, Giuliana Parisi, Isabel Medina   +5 more
wiley   +1 more source

Unveiling nuclear localization signals in human arginine deiminase proteins

Protein Science, Volume 35, Issue 4, April 2026.
Abstract Arginine iminohydrolases are a family of enzymes involved in the conversion of arginine to citrulline. There are five isoforms in humans (PADI1, 2, 3, 4, and 6). Some of them are observed experimentally in the cytoplasm and in the nucleus of the cell; for moving to the latter location, they must pass through the cell nuclear membrane by using ...
José L. Neira, Olga Abian, Adrián Velazquez‐Campoy, Bruno Rizzuti   +3 more
wiley   +1 more source

Glycolate oxidase isozymes are coordinately controlled by GLO1 and GLO4 in rice. [PDF]

PLoS ONE, 2012
Glycolate oxidase (GLO) is a key enzyme in photorespiratory metabolism. Four putative GLO genes were identified in the rice genome, but how each gene member contributes to GLO activities, particularly to its isozyme profile, is not well understood.
Zhisheng Zhang, Yusheng Lu, Liguang Zhai, Rongshu Deng, Jun Jiang, Yong Li, Zhenghui He, Xinxiang Peng   +7 more
doaj   +1 more source

isozyme

, 2014
Citation: 'isozyme' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.I03358 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial usage
openaire   +1 more source

Towards a Novel Biocontrol Strategy: High Performance of Optimised Cell Wall‐Degrading Enzymes Secreted by Escovopsis primorosea LBM 277

Environmental Microbiology Reports, Volume 18, Issue 2, April 2026.
Escovopsis primorosea LBM 277 efficiently produced proteases, β‐1,3‐glucanases and chitinases under submerged fermentation using Leucoagaricus gongylophorus cell walls and Mandels complex. RSM‐BBD optimization significantly increased enzyme activity. The enzymatic cocktail remained stable for 30 days at room temperature and pH 4–6, aligning with the ...
Marcela Paola Barengo, Natalia Soledad Amerio, Gustavo Ángel Bich, Pedro Darío Zapata, María Lorena Castrillo   +4 more
wiley   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, Volume 101, Issue 2, Page 751-803, April 2026.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source