Results 51 to 60 of about 69,433 (226)

Genetic diversity and population structure of pedunculate oaks (Quercus robur) in Wytham Woods

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Genetic diversity underpins forest resilience and adaptation, yet centuries of human activity have reshaped woodland ecosystems worldwide. We studied the population genetics of pedunculate oaks (Quercus robur) in Wytham Woods, UK, across stands with different ages and management histories.
Tin Hang Hung   +6 more
wiley   +1 more source

Glycolate oxidase isozymes are coordinately controlled by GLO1 and GLO4 in rice. [PDF]

open access: yesPLoS ONE, 2012
Glycolate oxidase (GLO) is a key enzyme in photorespiratory metabolism. Four putative GLO genes were identified in the rice genome, but how each gene member contributes to GLO activities, particularly to its isozyme profile, is not well understood.
Zhisheng Zhang   +7 more
doaj   +1 more source

Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.
Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo   +5 more
wiley   +1 more source

Minor Isozymes Tailor Yeast Metabolism to Carbon Availability

open access: yesmSystems, 2019
Isozymes are enzymes that differ in sequence but catalyze the same chemical reactions. Despite their apparent redundancy, isozymes are often retained over evolutionary time, suggesting that they contribute to fitness.
Patrick H. Bradley   +4 more
doaj   +3 more sources

Evidence that mitochondrial isozymes are genetically less variable than cytoplasmic isozymes

open access: yesGenetical Research, 1988
SummaryIt has been proposed that isoenzymes functioning within cell organelles (chloroplasts, mitochondria) are genetically less variable than their cytoplasmic counterparts, as a result either of constraints imposed by the need to cross organelle membranes or from the different and specialized nature of organelle metabolism.
David O. F. Skibinski, Robert D. Ward
openaire   +3 more sources

Drug‐Tolerant, Chemiluminescent Lateral Flow Immunoassay Platform for the Determination of Neutralizing Anti‐Drug Antibodies

open access: yesSmall, EarlyView.
Immunogenicity evaluation in patients receiving mAb therapy is becoming the standard of care in healthcare systems worldwide. Nevertheless, current methods for anti‐drug antibody determination suffer from drug interference and/or inability to be performed at the point‐of‐care (POC).
Frans Kokojka   +4 more
wiley   +1 more source

Paternity Analysis of Tea (Camellia sinensis L. Kuntz) Hybrids Using Isozyme Marker

open access: yesIndonesian Journal of Biotechnology, 2012
Tea plant has been categorized as self-incompatible crop. This is the reason behind the high genetic diversity. Natural pollination is possible to occur and the male parent is usually unknown, therefore, there is a need of method to identify male parent ...
Titin Setyorini   +3 more
doaj   +1 more source

Recent developments in the chemistry and enzyme inhibitory activity of fused thiazoles and thiadiazoles

open access: yesVietnam Journal of Chemistry, EarlyView.
Abstract The combination of cyclization reactions of thiadiazoles and benzothiazoles with Pd‐catalyzed cross‐coupling reactions provided a convenient synthesis of annulated, fluorinated and non‐fluorinated heterocycles, such as 1,3,4‐thiadiazolo[3,2‐a]pyrimidin‐5‐ones, benzothiazolo[3,2‐a]pyridimidin‐4‐ones, benzothiazolo[2,3‐b]quinazolin‐12‐ones and ...
Peter Langer
wiley   +1 more source

Lycium barbarum polysaccharides enhance testicular spermatogenesis in d‐galactose‐induced aging rats via calcium signaling

open access: yesAndrology, EarlyView.
Abstract Background Lycium barbarum polysaccharide (LBP) has long been recognized as having a wide range of beneficial properties for improving proliferation. However, the protective effects and specific mechanisms of d‐galactose‐induced testicular dysfunction in reproductively senescent rats are not fully understood.
Wenxin Ma   +8 more
wiley   +1 more source

Plantlet regeneration and somaclonal variation in Anthurium cv. Sultan through embryogenesis [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2007
Calli of anthurium cv. Sultan were cultured on liquid or solid MMS (modified Murashige and Skoog) medium. The solid medium was supplemented with 1.0-4.0 mg/l 2,4-D (2,4-dichlorophenoxyacetic acid) incombination with 0.5 and 1.0 mg/l kinetin or 0.5, 0.75 ...
Te-chato, S., Sontikul, Y.
doaj  

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