Results 61 to 70 of about 69,433 (226)
Na,K-ATPase isozymes in colorectal cancer and liver metastases
Frontiers in Physiology, 2016 The goal of this study was to define Na,K-ATPase α and β subunit isoform expression and isozyme composition in colorectal cancer cells and liver metastases.
Marc eBaker Bechmann +10 more
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British Journal of Haematology, EarlyView.Summary Ibrutinib is metabolized by cytochrome P450 3A (CYP3A) and poses challenges with drug interactions. We conducted a population‐based cohort study of Ontario residents aged ≥66 years who initiated ibrutinib for chronic lymphocytic leukaemia (CLL) to evaluate the frequency of potential drug interactions involving moderate/strong CYP3A inhibitors ...
Tuan Hoang +10 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Dysregulation of the IL‐6/glycoprotein 130(gp130)/STAT3 signalling axis is implicated in several human diseases, particularly cancer. Notably, gp130, a single transducer of this signalling axis, is a target for ovarian cancer treatment. However, data regarding small‐molecule inhibitors of gp130 are lacking. Therefore, we aimed to
Sun‐Ae Park +11 more
wiley +1 more source
Role of Histone Deacetylase and Inhibitors in Cardiovascular Diseases
Cell Proliferation, EarlyView.HDACs play an important role in the occurrence and development of cardiovascular diseases, such as myocardial hypertrophy, hypertension, and atherosclerosis. HDAC inhibitors have broad prospects for the treatment of CVD, and different HDAC subtypes can act through different mechanisms.
Li‐Ying Zhang +4 more
wiley +1 more source
Aluminium induced esterase activity and isozyme pattern in barley root tip
Plant, Soil and Environment, 2005 Changes in the activity of esterase as well as changes in the viability of root cells and some growth parameters were analysed during cultivation of barley seedlings in the artificial substrate under Al stress conditions.
L. Tamás +4 more
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The FEBS Journal, EarlyView.Enzymes from the phosphodiesterase type 4 family (PDE4) coordinate physiological events driven by the cyclic AMP s(cAMP) signaling pathway by tightly controlling cAMP dynamics in many cell types. Key to this strict regulation is the myriad of posttranslational modifications that alter PDE4 activity, cellular location, and binding partner selection ...
Madihah Hussain +2 more
wiley +1 more source
Banana breeding by genome design
Journal of Integrative Plant Biology, EarlyView.ABSTRACT Bananas and plantains of the genus Musa constitute the most vital fruits and staple foods. Cultivated bananas may have originated from intraspecific and interspecific hybridizations of four wild species, namely Musa acuminata (A), M. balbisiana (B), M. schizocarpa (S), and the Australimusa species (T).
Rida Arshad +13 more
wiley +1 more source
Molecular Ecology, EarlyView.ABSTRACT Many ant species show dramatic shifts in behaviour when infected with parasites, but the molecular basis of these behavioural changes is not well understood. An example is the wood ant, Formica aserva, which serves as an intermediate host for the lancet liver fluke, Dicrocoelium dendriticum.
Chen‐Hua Li +2 more
wiley +1 more source
Isozymes of lactic dehydrogenase in human tissues [PDF]
, 1961 Elliot S. Vesell, Alexander G. Bearn
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Substrate specificity of glucokinase and fructokinase of several conifer species
Acta Societatis Botanicorum Poloniae, 2014 Annual plant species were found to have several distinct classes of hexokinases which are specific for different hexoses, such as glucose, fructose and mannose.
Fritz Bergmanni, Leon Mejnartowicz
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