Fragment Discovery by X-Ray Crystallographic Screening Targeting the CTP Binding Site of Pseudomonas Aeruginosa IspD. [PDF]
With antimicrobial resistance (AMR) reaching alarming levels, new anti‐infectives with unprecedented mechanisms of action are urgently needed. The 2‐C‐methylerythritol‐D‐erythritol‐4‐phosphate (MEP) pathway represents an attractive source of drug targets
Willocx D +8 more
europepmc +2 more sources
Dystroglycanopathy, a subgroup of muscular dystrophies, is characterized by hypoglycosylation of α-dystroglycan (α-DG), which reduces its laminin-binding activity to extracellular matrix proteins, causing progressive loss of muscle integrity and function.
Marcela P. Cataldi +4 more
doaj +1 more source
Informations concernant cette traduction Dans le cadre d’un accord de partenariat entre l’ISPD et le RDPLF, le RDPLF est le traducteur français officiel des recommandations de l’ISPD (https://doi.org/10.25796/bdd.v4i3.63033).
Max Dratwa, Christian Verger
doaj +1 more source
Establishing a core outcome set for peritoneal dialysis : report of the SONG-PD (standardized outcomes in nephrology-peritoneal dialysis) consensus workshop [PDF]
Outcomes reported in randomized controlled trials in peritoneal dialysis (PD) are diverse, are measured inconsistently, and may not be important to patients, families, and clinicians.
Abraham, Georgi +118 more
core +2 more sources
The International Surface Pressure Databank version 2 [PDF]
The International Surface Pressure Databank (ISPD) is the world's largest collection of global surface and sea-level pressure observations. It was developed by extracting observations from established international archives, through international ...
Allan, Robert J. +45 more
core +2 more sources
Structure based de novo design of IspD inhibitors as anti-tubercular agents [PDF]
Tuberculosis is one of the leading contagious diseases, caused by Mycobacterium tuberculosis. Despite improvements in anti-tubercular agents, it remains one of the most prevalent infectious diseases worldwide, responsible for a total of 1.6 million ...
Abhay T. Sangamwar +4 more
core +2 more sources
Créer et maintenir un accès péritonéal optimal chez les patients adultes : mise à jour 2019
En avril 2019 la Société Internationale de Dialyse Péritonéale a publié en "open access" ses dernières recommandations pour créer et maintenir un abord péritonéal optimal chez les patients adultes.
Max Dratwa, Christian Verger
doaj +1 more source
The main genetic locus associated with the evolution of gamecocks is centered on ISPD
Chickens were domesticated >4,000 years ago, probably first for fighting them and only later as a source of food. Fighting chickens, commonly known as gamecocks, continue to be bred throughout the world, but the genetic relationships among geographically
Andrés Bendesky +6 more
semanticscholar +1 more source
Preserving Established Communications in IPv6 Multi-homed Sites with MEX [PDF]
This research was supported by the SAM (Advanced Mobility Services) project, funded by the Spanish National R&D Programme under contract MCYT TIC2002-04531-C04-03.A proper support for multimedia communications transport has to provide fault tolerance ...
Azcorra, Arturo +4 more
core +3 more sources
Transgenic Rescue of the LARGEmyd Mouse: A LARGE Therapeutic Window? [PDF]
LARGE is a glycosyltransferase involved in glycosylation of α-dystroglycan (α-DG). Absence of this protein in the LARGEmyd mouse results in α-DG hypoglycosylation, and is associated with central nervous system abnormalities and progressive muscular ...
A Brancaccio +54 more
core +8 more sources

