Results 51 to 60 of about 7,686 (214)

The functional O-mannose glycan on adystroglycan contains a phospho-ribitol primed for matriglycan addition [PDF]

, 2016
This work was supported in part by grants from NIGMS/NIH (R01GM111939 to LW, P01GM107012, KWM and LW co-PIs), technology resource grants from NIGMS/NIH (P41GM103490, LW and KWM co-PIs and P41GM103390, KWM, PI), a Paul D.
Adzhubei, Baddiley, Barb, Barresi, Baur, Beckett, Beltrán-Valero de Bernabé, Carmignac, Chiba, Cirak, Collins, Damerell, Dobson, Dong, Duclos, Endo, Endo, Ervasti, Ervasti, Fakhouri, Geis, Hara, Hara, Holt, Jae, Kanagawa, Kumagai, Lee, Lee, Lee, Lefeber, Link, Manzini, Meng, Michele, Muntoni, Parsons, Perl, Praissman, Praissman, Pédelacq, Richard, Riemersma, Riemersma, Robu, Roscioli, Sim, Stalnaker, Stalnaker, Tözsér, Vester-Christensen, Vuillaumier-Barrot, Wells, Willer, Willer, Yoshida, Yoshida, Yoshida-Moriguchi, Yoshida-Moriguchi, Yoshida-Moriguchi   +59 more
core   +2 more sources

ISPD produces CDP-ribitol used by FKTN and FKRP to transfer ribitol phosphate onto α-dystroglycan

Nature Communications, 2016
Mutations in genes required for the glycosylation of α-dystroglycan lead to dystroglycanopathies. Here, the authors show that three of these enzymes (ISPD, FKTN and FKRP) work together to attach ribitol phosphate to α-dystroglycan.
Isabelle Gerin, Benoît Ury, Isabelle Breloy, Céline Bouchet-Seraphin, Jennifer Bolsée, Mathias Halbout, Julie Graff, Didier Vertommen, Giulio G. Muccioli, Nathalie Seta, Jean-Marie Cuisset, Ivana Dabaj, Susana Quijano-Roy, Ammi Grahn, Emile Van Schaftingen, Guido T. Bommer   +15 more
doaj   +1 more source

Molecular Mechanism of Action of Antimalarial Benzoisothiazolones: Species-Selective Inhibitors of the Plasmodium spp. MEP Pathway enzyme, IspD [PDF]

, 2016
The methylerythritol phosphate (MEP) pathway is an essential metabolic pathway found in malaria parasites, but absent in mammals, making it a highly attractive target for the discovery of novel and selective antimalarial therapies.
Armstrong, CM, Berry, NG, Hodge, DM, Imlay, LS, Lawrenson, AS, Mikati, M, O'Neill, PM, Odom John, AR, Park, J, Pidathala, C, Price, KE, Roberts, NJ, Sharma, R, Tolia, NH   +13 more
core   +1 more source

Investigación sobre la práctica docente en las universidades

Cuaderno de Pedagogía Universitaria, 2014
La investigación sobre la práctica docente (ISPD) en el contexto universitario es un estudio crítico de la docencia que busca reflexionar sobre esta para mejorar su incidencia en la calidad del aprendizaje de los estudiantes. Este artículo se basa en la
Martha E. Báez
doaj   +1 more source

Ranking Departments based on research quality: a statistical evaluation of the ISPD indicator

Scientometrics
Given the relevance of performance-based funding for the Italian University System, in this paper, we analyse the statistical properties of the ISPD indicator used to provide a ranking of the best 180 Italian Departments.
F. Galli, Fedele Greco
semanticscholar   +1 more source

Vancomycin in peritoneal dialysis: Clinical pharmacology considerations in therapy. [PDF]

, 2020
Intraperitoneal vancomycin is the first-line therapy in the management of peritoneal dialysis (PD)-related peritonitis. However, due to the paucity of data, vancomycin dosing for peritonitis in patients on automated peritoneal dialysis (APD) is empiric ...
Kraft, Walter K., Lam, Edwin, Lien, Yi Ting Kayla, Piraino, Beth, Schmidt, Stephan, Vozmediano, Valvanera, Zhang, Jingjing   +6 more
core   +1 more source

Triple Patterning Lithography (TPL) Layout Decomposition using End-Cutting

, 2013
Triple patterning lithography (TPL) is one of the most promising techniques in the 14nm logic node and beyond. However, traditional LELELE type TPL technology suffers from native conflict and overlapping problems.
Gao, Jhih-Rong, Pan, David Z., Yu, Bei
core   +1 more source

Global Delivery of Foetal Sequencing: Do We Need Some Standardisation?

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective The development of sequencing technologies has resulted in rapid expansion in the testing available for foetuses with structural anomalies to diagnose monogenic disorders. To understand the variability in how foetal sequencing services are delivered, we developed a survey that focussed on the scope of testing, any parallel testing ...
Natalie J. Chandler, Zandra C. Deans
wiley   +1 more source

Traduction française de «L’activité physique et l’exercice en dialyse péritonéale : recommandations pratiques de la Société Internationale pour la Dialyse Péritonéale (ISPD)et le réseau Peritoneal Dialysis and the Global Renal Exercise.»

Bulletin de la Dialyse à Domicile, 2022
Informations concernant cette traduction Dans le cadre d’un accord de partenariat entre l’ISPD et le RDPLF, le RDPLF est le traducteur français officiel des recommandations de l’ISPD.
Christian Verger, Max Dratwa
doaj   +1 more source

Yield of Whole Genome Sequencing for Pathogenic Single Nucleotide Variants in Congenital Heart Disease: A Systematic Review and Meta‐Analysis

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis aimed to assess the diagnostic yield of pathogenic or likely pathogenic (P/LP) single nucleotide variants (SNVs) using whole genome sequencing (WGS) in congenital heart disease (CHD). Methods A systematic search of three databases (2000–2024) was conducted, and two reviewers independently ...
Hiba J. Mustafa, Parisa Najjariasl, Faezeh Aghajani, Enaja V. Sambatur, Andrew Rodenbarger, Stephanie Guseh, Amy E. Roberts, Alireza A. Shamshirsaz   +7 more
wiley   +1 more source