Results 201 to 210 of about 1,666,973 (292)

Investigation of the Prevalence of Associated Genetic Mutations (Co-Mutations) in Patients with Actionable Driver Mutations in Lung Cancer: A Retrospective Study. [PDF]

open access: yesDiagnostics (Basel)
Agbarya A   +9 more
europepmc   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher   +7 more
wiley   +1 more source

Paternal use of metformin and risk of major congenital malformations: A meta‐analysis of 4 studies

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Metformin is the first‐line drug for the treatment of Type 2 diabetes. In 2022, a Danish registry‐based study reported a 40% increased risk of major congenital malformations following paternal exposure during spermatogenesis. This raised widespread concern about the use of metformin in males of reproductive age.
Per Damkier   +7 more
wiley   +1 more source

Advanced therapy medicinal products (ATMPs) – An analysis of the global regulatory status

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Background A rapid progress in the development of advanced therapy medicinal products (ATMPs) has taken place over the past decades. The ATMPs hold great potential but face challenges in the clinical development and the regulatory process.
Allan Cramer   +4 more
wiley   +1 more source

Clinical Impact of Routine HBV Screening in Oncologic Patients Prior to Chemotherapy. [PDF]

open access: yesJ Clin Med
Abu Sini H   +7 more
europepmc   +1 more source

Activism as education in and through the youth climate justice movement

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Young people worldwide are increasingly participating in a global movement for climate justice, yet to date, little research has examined how youth climate justice activists conceive of and experience activism as education. The present study used in‐depth, semi‐structured interviews with 16 US climate justice activists (aged 15–17) to address ...
Carlie D. Trott
wiley   +1 more source

Operationalising global education in teacher education and training: A model for contextualising terminology

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Despite a growing international consensus that students need to be provided with the type of education that effectively prepares them to engage in and contribute to their globalised world, and that teachers need to be appropriately trained to facilitate this teaching and learning, ‘global education’ continues to be hindered by a lack of ...
Sarah‐Louise Jones   +2 more
wiley   +1 more source

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