Results 281 to 290 of about 1,984,093 (365)

Recurrence Risk in Pediatric Noninfectious Uveitis During Adalimumab Tapering: An International Multicenter Retrospective Study

open access: yesArthritis &Rheumatology, EarlyView.
Objective This study aims to assess the risk of noninfectious uveitis (NIU) relapse in pediatric patients undergoing adalimumab (ADA) tapering, evaluating potential predictors of such risk. Methods We conducted a multicenter retrospective cohort study involving pediatric patients with NIU who underwent ADA tapering due to inactive uveitis.
Achille Marino   +31 more
wiley   +1 more source

Aberrant Glycosylation of IgG in Children With Active Lupus Nephritis Alters Podocyte Metabolism and Causes Podocyte Injury

open access: yesArthritis &Rheumatology, EarlyView.
Objective Podocytes are integral to the maintenance of the glomerular filtration barrier. Their injury results in proteinuria and disease progression in lupus nephritis (LN). Aberrant IgG glycosylation drives podocyte injury in LN and leads to cytoskeletal rearrangement, motility changes, and decreased nephrin production.
Rhea Bhargava   +9 more
wiley   +1 more source

Paradoxical Activation of Entheseal Myeloid Cells by JAK1 and Tyk2 Inhibitors via Interleukin‐10 Antagonism

open access: yesArthritis &Rheumatology, EarlyView.
Objective JAK inhibition (JAKi) is effective in seronegative spondyloarthropathy (SpA) spectrum disorders, but Tyk2 inhibition failed in SpA spectrum ulcerative colitis, and tofacitinib showed minimal benefit in Crohn disease, which highlights the complex role for JAK/STAT signaling in different inflammatory processes.
Sami Giryes   +14 more
wiley   +1 more source

Efficacy and Safety of ABBV‐154 for the Treatment of Active Rheumatoid Arthritis: A Phase 2b, Randomized, Placebo‐Controlled Trial

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Despite availability of biologics and targeted synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs) to treat rheumatoid arthritis (RA), many patients do not experience optimized disease control. Glucocorticoids are effective but have safety risks.
Frank Buttgereit   +13 more
wiley   +1 more source

Spiritual and religious information experiences: An Annual Review of Information Science and Technology (ARIST) paper

open access: yesJournal of the Association for Information Science and Technology, EarlyView.
Abstract This chapter examines the contours of the religious and spiritual information experiences subfield through a review and content analysis of selected contributions from the past two decades in both information science and related fields. The research question that guides this review is: How have spirituality and religion been conceptualized in ...
Nadia Caidi   +4 more
wiley   +1 more source

Toward information resilience: Applying intersectionality to the HIV/AIDS information practices of Black sexual minority men

open access: yesJournal of the Association for Information Science and Technology, EarlyView.
Abstract Using intersectionality as a critical theoretical framework and analytical tool, this study investigated the HIV/AIDS information practices of Black sexual minority men (SMM). Twenty‐two Black SMM were interviewed about their HIV/AIDS‐related information practices.
Megan Threats
wiley   +1 more source

Exploring the Impact of Gender and Age of Onset on Psoriasis Treatment Management. [PDF]

open access: yesJ Clin Med
Lax T   +8 more
europepmc   +1 more source

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