Results 81 to 90 of about 36,426 (180)

From Tumour to Bloodstream: Advancing PD‐L1 Testing With Liquid Biopsies in Non‐Small Cell Lung Cancer

open access: yesCytopathology, EarlyView.
This review explores liquid biopsy as a complementary approach to tissue‐based PD‐L1 assessment in advanced NSCLC treated with immune checkpoint inhibitors. Focusing on circulating tumour cells, extracellular vesicles, and circulating tumour DNA, it summarises current evidence, technical challenges, and future perspectives for personalised ...
R. Leporati   +15 more
wiley   +1 more source

Early neurodevelopmental outcome in newborns with mild hypoxic‐ischaemic encephalopathy

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Aim To describe the natural history of newborn children with mild hypoxic‐ischaemic encephalopathy in the first year of life. Method This was a multicentre, prospective observational study involving five neonatal intensive care units in an Italian region using both structured clinical and neurophysiological assessments according to the Italian Society ...
Domenico M. Romeo   +16 more
wiley   +1 more source

Chasing the perfida Albione: Anglo‐Italian productivity gap in the late 1930s

open access: yesThe Economic History Review, EarlyView.
Abstract This paper presents new estimates of Anglo‐Italian labour productivity levels in manufacturing in the late 1930s, derived using the standard single‐deflation approach. The findings confirm a substantial productivity gap between Italy and the United Kingdom at the aggregate level, alongside pronounced intersectoral heterogeneity.
Tancredi Salamone
wiley   +1 more source

Unraveling in vitro phase separation and aggregation properties of the structured region of FMRP and the impact of Fragile X syndrome‐linked mutations

open access: yesThe FEBS Journal, EarlyView.
Fragile X messenger ribonucleoprotein 1 (FMRP) is a multidomain RNA‐binding protein associated with Fragile X Syndrome (FXS). We found that its N‐terminal structured region has an intrinsic propensity to undergo liquid–liquid phase separation and fibril formation. FXS‐associated mutations perturb protein stability and aggregation propensity, suggesting
Flavia Catalano   +10 more
wiley   +1 more source

Integrating environmental DNA, diving surveys and DNA barcoding to track endangered twaite shad (Alosa fallax) spawning sites

open access: yesJournal of Fish Biology, EarlyView.
Abstract The twaite shad (A. fallax), an anadromous fish species belonging to the Clupeidae family, has experienced population declines throughout Europe. This decline is attributable to a range of anthropogenic pressures, including migration barriers, environmental pollution, habitat degradation, predation by invasive species and unsustainable fishing
Alessia Ardenghi   +10 more
wiley   +1 more source

Theorizing Waste as a Technique of Power in Capitalistic Stakeholder Relations

open access: yesJournal of Management Studies, EarlyView.
Abstract Waste is an important socio‐ecological challenge of contemporary capitalism, contributing to climate change and environmental degradation. Despite its pervasiveness and its impacts on diverse stakeholders, it yet remains largely underexplored in management and organization studies.
Elise Lobbedez   +2 more
wiley   +1 more source

Itália

open access: yesMeridiano 47, 2017
O presente artigo busca delinear os impactos políticos e conseqüências internacionais e regionais da ascensão de Silvio Berlusconi ao cargo de primeiro-ministro italiano.
VIRGILIO ARRAES
doaj  

Oral and Pancreatobiliary Microbiota in Cancer: A Systematic Review of Compositional Alterations and Their Clinical Implications

open access: yesJournal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Associations between microbial dysbiosis and malignancies of the pancreatobiliary system have been described in recent studies. As a result of the limited number of studies that have been done specifically on the malignancies of the biliary tract, information regarding oral, biliary and tumour‐related microbial alterations was ...
Esperouz Fariba   +5 more
wiley   +1 more source

Soft Tissue Substitutes: Current Biomaterials and Indications at Teeth and Implant Sites

open access: yesJournal of Periodontal Research, EarlyView.
This manuscript provides an updated overview of the current evidence on soft tissue graft substitutes for teeth and dental implants. When appropriately indicated, these biomaterials offer a reliable, less invasive alternative to autogenous grafts, effectively improving root coverage, keratinized mucosa width, and soft tissue thickness with reduced ...
Lorenzo Tavelli   +4 more
wiley   +1 more source

Biologically‐Oriented Alveolar Ridge Preservation (BARP) in Intact and Compromised Extraction Sockets

open access: yesJournal of Periodontal Research, EarlyView.
The Biologically‐oriented Alveolar Ridge Preservation (BARP) is an innovative technique characterized by the stratification of different biomaterials (collagen sponge and xenograft) at intact and compromised sockets. In both groups, the hard and soft tissue modification (bone width, bone height, tissue profile, and hard tissue composition) was limited.
Mattia Pramstraller   +7 more
wiley   +1 more source

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