Results 101 to 110 of about 56,280 (306)

Occupational orientation in chemistry-based learning environments

open access: yesLUMAT, 2015
The research presented in this paper describes the German project “Career and Science Navigator (CSN)”. This project ties in with previous studies, which indicate that it is necessary to include occupational orientation more strongly into science ...
Michael Albertus, Claus Bolte
doaj   +1 more source

The Effectiveness of Group Guidance with Modelling in Increasing The Maturity of Career Choice

open access: yesInternational Journal of Research in Counseling and Education, 2018
The maturity of the career choice direction becomes a central idea in the career development of the students. There are still many students who are less thorough in understanding career information. Therefore, the purpose of this study is to look at the effectiveness of group counseling services with modelling in improving student career choices.
Sisri Wahyuni   +2 more
openaire   +3 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Protean and Boundaryless Career Attitudes in New Zealand Workers [PDF]

open access: yes, 2010
This study explored protean and boundaryless career attitudes in a sample of New Zealand workers. Recent changes to both organisational and societal structures have significantly altered how careers are acted out.
Morrell, Heather Rebecca
core  

MUSLIMAH MOMPRENEUR DALAM MAJALAH KELUARGA ISLAM HADILA (Solusi Alternatif Dilema Peran Ekonomi Perempuan dalam Keluarga Sakinah)

open access: yesJurnal SMART (Studi Masyarakat, Religi, dan Tradisi), 2018
Women’s dilemma between career and family is one of the prominent discourses on sakinah family development today that needs to solve. This paper analyzes the concept of Hadila Islamic family magazine, as one of the tarbiyah movement representations, on ...
Sidik Sidik
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Altered positions: a study on the expectations and experiences of career mentoring in higher education [PDF]

open access: yes, 2014
This thesis investigates a specific instance of mentoring offered to final year HE design students in order to propose that ‘readiness for mentoring’ is a theory worthy of expansion and that this expansion can add to the field of knowledge on mentoring ...
Hayton, Kavita
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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