Results 51 to 60 of about 4,115,069 (292)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Low-Latency and Low-Randomness Second-Order Masked Cubic Functions

open access: yesTransactions on Cryptographic Hardware and Embedded Systems, 2022
Masking schemes are the most popular countermeasure to mitigate Side-Channel Analysis (SCA) attacks. Compared to software, their hardware implementations require certain considerations with respect to physical defaults, such as glitches. To counter this
Aein Rezaei Shahmirzadi   +2 more
doaj   +1 more source

Usable Security: Why Do We Need It? How Do We Get It? [PDF]

open access: yes, 2005
Security experts frequently refer to people as “the weakest link in the chain” of system security. Famed hacker Kevin Mitnick revealed that he hardly ever cracked a password, because it “was easier to dupe people into revealing it” by employing a range
Flechais, I, Sasse, MA
core  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

IT convergence security [PDF]

open access: yesJournal of Intelligent Manufacturing, 2013
A recent emerging issue in information technology is the convergence of different kinds of applications. Convergence brings a user-centric environment to provide computing and communication services. In order to realize IT advantages, it requires the integration of security and data management to be suitable for pervasive computing environments ...
Hangbae Chang   +2 more
openaire   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Spin Me Right Round Rotational Symmetry for FPGA-Specific AES

open access: yesTransactions on Cryptographic Hardware and Embedded Systems, 2018
The effort in reducing the area of AES implementations has largely been focused on Application-Specific Integrated Circuits (ASICs) in which a tower field construction leads to a small design of the AES S-box.
Lauren De Meyer   +2 more
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

UP TO 50% OFF: Efficient Implementation of Polynomial Masking

open access: yesTransactions on Cryptographic Hardware and Embedded Systems
While passive probing attacks and active fault attacks have been studied for multiple decades, research has only started to consider combined attacks that use both probes and faults relatively recently.
Jorge Andresen   +11 more
doaj   +1 more source

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