Results 61 to 70 of about 7,289,458 (298)
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Aging and Cancer, EarlyView.Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi +3 more
wiley +1 more source
With rhymes about the human fate. Philosophy in the poetry of Giacomo Leopardi
Acta Universitatis Lodziensis. Folia Litteraria Polonica, 2020 Giacomo Leopardi is one of those authors whose texts oscillate on the border between literature and philosophy. It is true that Leopardi does not use traditional forms of philosophical expression, but the fact is that most of the considerations of the ...
Aleksandra Koman
doaj +1 more source
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants
Annals of Clinical and Translational Neurology, EarlyView.Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source
HumanitiesEmanuele Tesauro’s Il cannocchiale aristotelico (The Spyglass of Aristotle) is widely considered a masterpiece of the Baroque, mainly because of his theory of metaphor as a cognitive tool. But this work is much more than that. Tesauro presents his volume
Teodoro Katinis
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A Mystic Analysis of Alda Merini’s Poetry [PDF]
پژوهشنامۀ انتقادی متون و برنامههای علوم انسانی, 2018 AldaMerini appearsamong those contemporary Italian poets translated into Persian. Merini is a poetess of great renown because her poetry leads readers to the knowledge of a world-wide aspect of literature.
Mohammad Hussein Ramezankiaei +1 more
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SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Leveraging Grey Literature – Capitalizing on Value and the Return on Investment
, 2016 The method of approach is a cumulative case study from 2003 onwards of a select number of information products and services provided by GreyNet. Each were introduced to serve the interests of the grey literature community and their production and supply ...
Farace, Dr. D. (GreyNet International, Grey Literature Network Service)
core +1 more source
Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan +14 more
wiley +1 more source
Il “Sogno” di un collezionista del Seicento napoletano. Maurizio Di Gregorio tra riscrittura e plagio [PDF]
Parole Rubate, 2011 Sogno and Rosario delle stampe de tutti i poeti e poetesse antichi e moderni di numero 500 by the Dominican friar and idle academic Maurizio Di Gregorio were published in Naples in 1614.
Daniela Caracciolo
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