ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser +5 more
wiley +1 more source
Changes in SMEs financing: risks and opportunities for agro-food companies
The financial and real crisis started in 2007-2008 has deeply transformed the way the Italian financial and capital market act. Italian SMEs need to be aware of the transformation not to be pushed out of the market itself and to take profit of the new ...
Giorgio Stefano Bertinetti
doaj +1 more source
The real problem in Italian democracy is not the electoral law, but Silvio Berlusconi’s continued grip over the country’s media [PDF]
Italy’s new prime minister Matteo Renzi has made electoral reform one of his key priorities, with a new electoral law currently under consideration in the Italian Senate, having been passed in the lower house of the Italian parliament last week ...
Larcinese, Valentino
core
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Outside income and moral hazard : the elusive quest for good politicians [PDF]
In most modern democracies elected officials can work in the private sector while appointed in parliament. We show that when the political and market sectors are not mutually exclusive, a trade-off arises between the quality of elected officials and ...
Gagliarducci, Stefano +2 more
core +2 more sources
Mining and Analyzing the Italian Parliament: Party Structure and Evolution
The roll calls of the Italian Parliament in the XVI legislature are studied by employing multidimensional scaling, hierarchical clustering, and network analysis.
AK Jain +13 more
core +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
About the prospects of European Eurosceptic political parties in the forthcoming all European elections 2019 [PDF]
European elections for the deputies of the European Parliament are to be held at the end of May 2019. An active role in these elections will be played by radical Eurosceptic party «The Movement for the Europe of Nations and Freedoms» led by the Leader ...
Boris Guseletov
doaj +1 more source
DON’T WASTE YOUR VOTE (AGAIN!). THE ITALIAN CONSTITUTIONAL COURT’S DECISION ON ELECTION LAWS: AN EPISODE OF STRICT COMPARATIVE SCRUTINY [PDF]
With a single judgment (sent. 1/2014), the Italian Constitutional Court has almost revolutionized Parliamentary election law, the national political landscape, the types of controversies with which it deals, and the means through which it reviews ...
LONGO, ERIK, PIN, ANDREA
core
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source

