Results 121 to 130 of about 1,432,370 (262)

Caregiver Perspectives on the Burden of Disease and Treatment in Uncontrolled Gout

Arthritis Care &Research, EarlyView.
Objective Uncontrolled gout (UG) refers to persistently elevated serum urate (SU) levels >6 mg/dL and ongoing gout symptoms despite use of urate‐lowering therapy (ULT). The objective of this study was to evaluate the burden associated with informal caregiving for individuals with UG.
Angelo Gaffo, Bhavisha Desai, Abiola Oladapo, Nana Kragh, Rebekah Zincavage, Brad Padilla, Naomi Schlesinger   +6 more
wiley   +1 more source

Clinical Implications of Stroke Progressor Phenotypes defined based on ASPECTS decay and perfusion estimated infarct growth rate: insights from a large national thrombectomy registry. [PDF]

Neurol Sci
Ciacciarelli A, Nicolini E, Saia V, Pracucci G, Pensato U, De Michele M, Benedetti L, Casetta I, Fainardi E, Marcheselli S, Da Ros V, Maestrini I, Simonetti L, Zini A, Vinci SL, La Spina P, Laiso A, Nencini P, Del Sette B, Markushi TB, Bracco S, Tassi R, Saletti A, De Vito A, Boghi A, Naldi A, Burdi N, Boero G, Vallone S, Bigliardi G, Lazzarotti GA, Giannini N, Milazzo N, Persico A, Ruggiero M, Longoni M, Menozzi R, Pezzini A, Allegretti L, Tassinari T, Mambrin F, Cappellari M, Bergui M, Bosco G, Comai A, Franchini E, Lozupone E, Caggiula M, Zimatore S, Petruzzellis M, Gallesio I, Ferrandi D, Perri M, De Santis F, Puglielli E, Casalena A, Galvano G, Saracco E, Allegritti M, Caproni S, Alberti M, Invernizzi P, Carità G, Russo M, Besana M, Giossi A, Filizzolo M, Mannino M, Pelle G, Alessiani M, Konda D, Sallustio F, Mangiafico S, Toni D.   +73 more
europepmc   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Correction: Triglyceride-Glucose Index and Mortality Risk in the General Population: A Systematic Review and Meta-analysis of Prospective Studies. [PDF]

High Blood Press Cardiovasc Prev
D'Elia L, Stranges S, La Fata E, Fortunato F, Palladino R, Rendina D, Galletti F.   +6 more
europepmc   +1 more source

Characterization of Defect Distribution in an Additively Manufactured AlSi10Mg as a Function of Processing Parameters and Correlations with Extreme Value Statistics

Advanced Engineering Materials, EarlyView.
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt, Varma Kvvssn, Hossein Laieghi, Zia Uddin, Peyman Ansari, E. Kıvanç Sadak, Can Barış Toprak, Hüseyin Kızıl, Enrico Salvati   +8 more
wiley   +1 more source

Correction: Molecular subtypes and the (in vitro) response of glioblastoma to temozolomide. [PDF]

BJC Rep
Rancati S, Campolungo M, Duarte Dalmolin G, Lau P, Furia F, Coppe A, Landuzzi F, Vecchi M, Cavalli A, Gustincich S, Tirelli N.   +10 more
europepmc   +1 more source

The PRIMA Thesaurus for Materials Science and Engineering

Advanced Engineering Materials, EarlyView.
The PRIMA Thesaurus is a structured vocabulary designed to improve how materials science data is described and shared. Developed with input from multiple experts, it enables clear documentation of research workflows, data exchange, and reuse across platforms.
Rossella Aversa, Alexey Boubnov, Dario De Angelis, Catriona Eschke, Maximilian Kabbe, Felix Kraus, Mirco Panighel, Richard Thelen, Davide Valentinis   +8 more
wiley   +1 more source

Mortality Attributable to Hepatitis B and C in Italy, Romania, and Spain, 2022 Estimates. [PDF]

Liver Int
Korotych O, Thygesen HH, Mårdh O, Reyes-Urueña J, Marrone G, Rockstroh J, Jakobsen ML, de Martel C, Kondili LA, Quaranta MG, Mattioli B, Rosato S, Rendina M, De Feudis A, Cossiga V, Albano S, Morisco F, Viganò M, Loglio A, Fagiuoli S, Calvaruso V, Celsa C, Longobardi F, Coppola R, Russo FP, Battistella S, Coppola N, Sagnelli C, Coco B, Brunetto MR, Popovici O, Janță D, Calomfirescu C, Gheorghe LS, Ghioca M, Ester C, Chitul M, Cerban R, Trifan A, Huiban L, Muzica C, Popescu A, Sirli R, Nica C, Popa A, Ferret MB, Vargas-Accarino E, Díaz A, Méndez CF, Morano L, Alonso S, Ahumada A, Cañizares RB, Raben D, Duffell E.   +54 more
europepmc   +1 more source

Comparison of Triply Periodic Minimal Surface Energy Absorbers Under Uniaxial Compressive Loading

Advanced Engineering Materials, EarlyView.
This study investigates LCD 3D printed Triply Periodic Minimal Surface (TPMS) structures as mechanical energy absorbers. By comparing various base designs and layered combinations under uniaxial compression, it identifies that a Diamond‐Gyroid sandwich structure offers superior performance.
Sergej Grednev, Noah‐Lean Roschlaub, Anne Jung   +2 more
wiley   +1 more source

An inverse probability of treatment weighted comparison between vedolizumab, ustekinumab, and tofacitinib in anti-TNF-experienced ulcerative colitis patients. [PDF]

Ther Adv Gastroenterol
Tursi A, Pasta A, Elisei W, Barberio B, Bertin L, Mocci G, Maconi G, Gravina AG, Pellegrino R, Bodini G, Papa A, Savarino EV, Italian Network for Inflammatory Bowel Diseases (IN-IBD).   +12 more
europepmc   +1 more source