Results 201 to 210 of about 3,275,659 (305)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

FIT Soul Fashion Show: 1983 part 3

The FIT Soul Club presents the 1983 Soul Fashion Show. Featuring work by student designers and alumni and a salute to club advisor, Clara Branch.

core  

Psychometric Validation of the Kazakh Version of the Patient Health Questionnaire-9 (PHQ-9). [PDF]

Healthcare (Basel)
Seksenbayev N, Moldagaliyev T, Zhamaliyeva L, Baspakova A, Baibussinova A, Yessimov N, Akkuzinova K, Toleuov Y, Zhakiyeva S, Kudaibergenova S, Inoue K.   +10 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Cross-Cultural Adaptation and Preliminary Psychometric Evaluation of the Malay Orthodontic Patient Satisfaction Questionnaire and Patient Satisfaction Following Fixed Orthodontic Treatment in Malaysia. [PDF]

Healthcare (Basel)
Shahrul AI, Ja Qi Y, Tan Jun Xue S, Wahab RMA, Syed Mohamed AMF.   +4 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Development of the global climate crisis risk perception scale (GCCRP-S): A validity and reliability study. [PDF]

PLoS One
Ozen N, Topbas M, Beyhun NE, Orhon EN, Altin A, Turhan S.   +5 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Psychometric Validation of the Spanish Version of the Sheffield Preference-Based Venous Leg Ulcer Questionnaire (SPVU-5D) in Patients With Venous Leg Ulcers. [PDF]

Int Wound J
Barbas-Monjo MÁ, Sánchez-Romero EA, Verdú-Soriano J, Cabrero García J, Cuenca-Zaldívar JN, Sillevis R.   +5 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source