Results 111 to 120 of about 17,370,281 (337)

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

A Comparison of Item Parameters across Item Types [PDF]

open access: yes, 2014
Seven item formats from a professional licensure examination program (n=4,706) were evaluated to determine whether there are significant differences in item parameter estimates based on item formats.
Applegate, Gregory M.
core   +1 more source

The Effect of the Ratio of Common Items and the Separation of Grade Distributions on the Precision of Vertical Scaling

open access: yesSAGE Open
In order to investigate the influence of separation of grade distributions and ratio of common items on the precision of vertical scaling, this simulation study chooses common item design and first grade as base grade.
Guangming Li, Zhengyan Liang
doaj   +1 more source

Item parameters dissociate between expectation formats: A regression analysis of time-frequency decomposed EEG data

open access: yesFrontiers in Psychology, 2014
During language comprehension, semantic contextual information is used to generate expectations about upcoming items. This has been commonly studied through the N400 event-related potential (ERP), as a measure of facilitated lexical retrieval.
Irene Fernández Monsalve   +3 more
doaj   +1 more source

An Experimental Design to Investigate Item Parameter Drift

open access: yesApplied Psychological Measurement
Methods for detecting item parameter drift may be inadequate when every exposed item is at risk for drift. To address this scenario, a strategy for detecting item parameter drift is proposed that uses only unexposed items deployed in a stratified random method within an experimental design. The proposed method is illustrated by investigating unexpected
Peter Baldwin   +5 more
openaire   +3 more sources

Statistical Bias in Maximum Likelihood Estimators of Item Parameters [PDF]

open access: yesPsychometrika, 1982
Asymptotic formulas are derived for the bias in the maximum likelihood estimators of the item parameters in the logistic item response model when examinee abilities are known. Numerical results are given for a typical verbal test for college admission.
openaire   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Psychometrics With R: A Review Of CRAN Packages For Item Response Theory [PDF]

open access: yes, 2013
In this paper we review the current state of R packages for Item Response Theory (IRT). We group the available packages based on their purpose and provide an overview of each package's main functionality.
Mair, Patrick   +2 more
core  

Bias and Linking Error in Fixed Item Parameter Calibration

open access: yesAppliedMath
The two-parameter logistic (2PL) item response theory (IRT) model is frequently applied to analyze group differences for multivariate binary random variables.
Alexander Robitzsch
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy