Results 51 to 60 of about 5,139 (262)
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
IFS-Based Image Reconstruction of Binary Images with Functional Networks
Mathematics, 2022 This work addresses the IFS-based image reconstruction problem for binary images. Given a binary image as the input, the goal is to obtain all the parameters of an iterated function system whose attractor approximates the input image accurately; the ...
Akemi Gálvez +6 more
doaj +1 more source
Aging and Cancer, EarlyView.This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha +4 more
wiley +1 more source
Inequalities for some iterated linear operators and their applications in approximation theory
Journal of Numerical Analysis and Approximation Theory, 2001 Some inequalities for the ”derivatives” of iterated linear operators will be presented, which will be applied for the investigation of degrees of approximation. Thus, with the application of the Laplacian we improve some classical results concerning the
Hans-Bernd Knoop, Xinlong Zhou
doaj +2 more sources
Integrating vehicle routing into intermodal service network design with stochastic transit times
EURO Journal on Transportation and Logistics, 2021 Service network design is an important optimization problem for intermodal freight transportation on a tactical level. It includes the decisions on choosing transportation modes and paths for commodities throughout the intermodal network.
Jan Philipp Müller +2 more
doaj +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Outlier Detection in Regression Using an Iterated One-Step Approximation to the Huber-Skip Estimator
Econometrics, 2013 In regression we can delete outliers based upon a preliminary estimator and re-estimate the parameters by least squares based upon the retained observations. We study the properties of an iteratively defined sequence of estimators based on this idea.
Søren Johansen, Bent Nielsen
doaj +1 more source
Sparse Approximation Via Iterative Thresholding [PDF]
2006 IEEE International Conference on Acoustics Speed and Signal Processing Proceedings, 2006 The well-known shrinkage technique is still relevant for contemporary signal processing problems over redundant dictionaries. We present theoretical and empirical analyses for two iterative algorithms for sparse approximation that use shrinkage. The GENERAL IT algorithm amounts to a Landweber iteration with nonlinear shrinkage at each iteration step ...
Herrity, Kyle K. +2 more
openaire +2 more sources
Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund +3 more
wiley +1 more source
Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew +11 more
wiley +1 more source