A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi +17 more
wiley +1 more source
Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs +7 more
wiley +1 more source
"Detail-Free Mechanism Design in Twice Iterative Dominance: Large Economies" [PDF]
This paper investigates unique implementation in large economies with incomplete information and interdependent values; we degenerate the common knowledge assumptions and assume that a central planner is unaware of the specifications of an environment ...
Hitoshi Matsushima
core
Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane +10 more
wiley +1 more source
The Iterative Design Process of an Explainable AI Application for Non-Invasive Diagnosis of CNS Tumors: A User-Centered Approach. [PDF]
Prince EW, Hankinson TC, Görg C.
europepmc +1 more source
The use of early design tools in engineering processes : a comparative case study [PDF]
Nowadays, product design is increasingly complex: not only must it answer customer needs through complex functions; it must also ensure traceability throughout the design process, keeping in mind that standards and stringent regulations must be complied ...
AOUSSAT, Améziane +4 more
core
The Multiple Sclerosis Severity Allele rs10191329A and Cognitive Function: A UK Biobank Study
ABSTRACT The genome‐wide association study of Multiple Sclerosis severity linked the genetic variant rs10191329A to long‐term disability and implicated brain resilience as a determinant of outcome. We hypothesised that rs10191329A might influence cognition in other neurological diseases and healthy controls.
Ioanna Zimianiti +5 more
wiley +1 more source
Theoretically Guided Iterative Design of the Sense2Quit App for Tobacco Cessation in Persons Living with HIV. [PDF]
Schnall R +8 more
europepmc +1 more source
Joint Iterative Decoding of Trellis-Based VQ and TCM
A joint video and channel coded system employing an iteratively decoded serial concatenation of a Vector Quantization (VQ) based video codec and a Trellis-Coded Modulation (TCM) scheme is proposed.
Yang, L.-L. +5 more
core +1 more source
Advancing Stroke Clinical Trials Using Community Engagement and Implementation Science Approaches
ABSTRACT Stroke clinical trials are essential for advancing stroke care but can face challenges with recruitment, retention, clinical relevance, and translation into real‐world practice. We propose that integrating community engagement and implementation science approaches into stroke trials can help address these needs.
Lesli E. Skolarus +2 more
wiley +1 more source

