FGF14 GAA Intronic Expansion in Unsolved Adult‐Onset Ataxia in the Care4Rare Canada Consortium
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Spinocerebellar ataxias (SCA) represent a clinically and genetically heterogeneous group of progressive neurodegenerative diseases with prominent cerebellar atrophy. Recently, a novel pathogenic repeat expansion in intron 1 of FGF14 was identified, causing adult‐onset SCA (SCA27B). We aimed to determine the proportion
Alexanne Cuillerier +20 more
wiley +1 more source
On the convergence of a new fourth-order method for finding a zero of a derivative
AIMS MathematicsOn the basis of Wang's method, a new fourth-order method for finding a zero of a derivative was presented. Under the hypotheses that the third and fourth order derivatives of nonlinear function were bounded, the local convergence of a new fourth-order ...
Dongdong Ruan, Xiaofeng Wang
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Dual‐Phase C‐11 PiB PET Images for Detecting Tau Pathology in Cerebral Amyloid Angiopathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Cerebral amyloid angiopathy (CAA) is a major cause of lobar intracerebral hemorrhage and cognitive dysfunction in the elderly, and frequently coexists with Alzheimer's disease and tau pathology. Dual‐phase 11C‐PiB PET detects amyloid deposition and cerebral perfusion changes and may have diagnostic value for identifying tau in CAA ...
Meng‐Ting Chiang +4 more
wiley +1 more source
Subthalamic Nucleus Oscillatory Characteristics in Meige, Cervical Dystonia and Generalized Dystonia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Deep brain stimulation offers a unique opportunity to record neural activity of the basal ganglia. While much work in dystonia has focused on the globus pallidus internus, expanding research to investigate subthalamic nucleus (STN) activity in various dystonia types is critical to provide a comprehensive understanding of dystonia ...
Zhu Guan‐Yu +14 more
wiley +1 more source
An iterative method of computing the eigenvalue and eigenvalues of a symmetric matrix [PDF]
, 1960 Miroslav Fiedler, Vlastimil Pták
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Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective [18F]EKZ‐001 is a positron emission tomography (PET) tracer targeting histone deacetylase 6 (HDAC6), an enzyme responsible for intracellular transport and clearance of misfolded proteins. HDAC6 modulation is a promising treatment strategy in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Greet Vanderlinden +15 more
wiley +1 more source
An iterative method for computing the generalized inverse of an arbitrary matrix [PDF]
, 1965 Adi Ben-Israel
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Arthritis Care &Research, EarlyView.Objective Targeted synthetic disease‐modifying antirheumatic drugs (tsDMARDs) have expanded the management of autoimmune diseases, including rheumatic diseases. As the use of these drugs grows, it is important to understand their effects on pregnancy.
Vienna Cheng +7 more
wiley +1 more source
Semilinear elliptic equations with dependence on the gradient
Electronic Journal of Differential Equations, 2012 In this article we consider elliptic equations whose nonlinear term depends on the gradient of the unknown. We assume that the nonlinearity has a asymptotically linear growth at zero and at infinity with respect to the second variable.
Guanggang Liu, Shaoyun Shi, Yucheng Wei
doaj
On the Iterative Method of Dynamic Programming on a Finite Space Discrete Time Markov Process [PDF]
, 1965 Barry W. Brown
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