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Stem Cell Differentiation Disperses Transcriptional Clusters via a Conserved Surface‐Condensate Trajectory

open access: yesAdvanced Science, EarlyView.
Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg   +18 more
wiley   +1 more source

An improved iterative back projection algorithm based on ringing artifacts suppression

Neurocomputing, 2015
In order to suppress and reduce the ringing artifacts of the IBP super resolution algorithm, an improved iterative back projection (IBP) reconstruction algorithm is presented in this paper. Firstly, two novel concepts, variation and local variance variation based on an adaptive analysis are introduced.
Xin Yang, Ruigang Yang
exaly   +2 more sources

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