Results 111 to 120 of about 17,941 (271)
Polycarbonate nanogels enable lipid‐free delivery of anti‐MFAP‐5 siRNA into cancer‐associated fibroblasts (CAF) in hepatocellular carcinoma. In a cirrhotic murine model, this approach silences MFAP‐5, reduces fibroblast activation, and suppresses tumor growth by inhibiting NOTCH/Hes1‐driven angiogenesis. CAF‐targeted MFAP‐5 RNAi and conserved signaling
Paul Schneider +20 more
wiley +1 more source
Covid-19 Travel Planner Mobile Application Design with Lean Product Process Framework. [PDF]
Tavichaiyuth N +4 more
europepmc +1 more source
This study employs longitudinal fluorescence imaging in transgenic mice to map post‐craniotomy cortical recovery. We identify distinct neuroimmune recovery phases: microglial structural inflammation peaks at ∼10 days, neuronal structural intensity peaks at ∼14 days and correlates with microglial activity, and functional network modularity is most ...
Guihua Xiao +13 more
wiley +1 more source
A Wearable Brain–Computer Interface for Mitigating Car Sickness via Attention Shifting
Car sickness poses a major challenge in vehicular travel, yet effective nonpharmacological solutions are scarce. We developed a wearable, closed‐loop mindfulness BCI that uses real‐time EEG‐based neurofeedback to shift attention away from motion‐induced discomfort. Validated in real‐car experiments involving >100$>100$ susceptible individuals, over 83%
Jiawei Zhu +14 more
wiley +1 more source
Family caregivers' itineraries of preschool children who survived leukemia: implications for primary healthcare nursing. [PDF]
Mattos CX +5 more
europepmc +1 more source
Recommendation of tourist itineraries with dependence on transport time
Cristina González-Navasa +3 more
openaire +1 more source
Cytoprotection Concepts for Ischemic Stroke in the Recanalization Era
This review provides detailed information on modern cytoprotective strategies for ischemic stroke in the context of recanalization therapies. It derives their rationale based on contemporary knowledge of stroke pathophysiology and discusses the role of advanced imaging approaches as well as concepts for novel clinical trial designs.
Johannes Boltze, Marc Fisher
wiley +1 more source
Borophene: Crucial Challenges and the Way Forward
This review explores the challenges and progress in borophene research, focusing on synthesis strategies, structural properties, and potential applications. It highlights key experimental breakthroughs, discusses theoretical insights into borophene's unique features, and addresses pathways for overcoming stability and scalability issues.
Zhixuan Li +3 more
wiley +1 more source
Effects of european emissions trading system application to non EU airlines.
The European Union requires the application of an Emission Trading System (ETS) to all the flights arriving to or departing from EU airports beginning on 1 st of January 2012, according to the rules published in the Directive 2008/101/EC.
Benito Ruiz de Villa, Arturo
core
Emerging evidence suggests that intraneuronal Aβ accumulation represents an early pathogenic event in Alzheimer's disease (AD). Using Drosophila AD model, this study shows that a nonsecreted serine protease Yip7 physically interacts with Aβ. This causes intraneuronal Aβ accumulation but surprisingly reduces the associated neurotoxicity, arguing that ...
Jingyun Su +4 more
wiley +1 more source

