Results 181 to 190 of about 499,659 (323)

Super‐Response to Guselkumab Treatment in Patients With Moderate‐to‐Severe Psoriasis: Real‐World Data With Up to Five Years of Follow‐Up in The Czech Republic

open access: yesInternational Journal of Dermatology, EarlyView.
Super‐response to Guselkumab. ABSTRACT Background Guselkumab, a selective interleukin (IL)‐23 inhibitor, is approved for the treatment of moderate‐to‐severe plaque psoriasis. While randomized clinical trials have introduced the concept of “super‐responders” (SRe)—patients achieving complete skin clearance (Psoriasis Area and Severity Index [PASI] 100 ...
Martina Kojanova   +76 more
wiley   +1 more source

scRNA‐Seq reveals anti‐lymphoma immune responses in mogamulizumab‐associated skin eruptions

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
CCR4 was expressed in malignant clones and regulatory T cells in untreated CTCL, that were decreased in MAR. Malignant clones in MAR showed a silenced phenotype with decreases in central memory markers SELL and CCR7, and GTP‐binding member GIMAP7 and upregulation of MMP2 inhibitor TIMP2 and tumour suppressor gene RUNX3.
Shannon Meledathu   +13 more
wiley   +1 more source

Development and Validation of a Viability RT‐qPCR Assay for Detecting Infectious Spring Viraemia of Carp Virus (SVCV)

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT Spring viremia of carp virus (SVCV) is a contagious pathogen associated with significant mortality and economic losses in freshwater aquaculture. Although reverse transcription quantitative PCR (RT‐qPCR) enables rapid detection, it does not distinguish between infectious and non‐infectious viral particles, which may lead to overestimation of ...
Ha‐Jeong Son   +9 more
wiley   +1 more source

Occlusal Sensitivity to Articulating Foils in Patients With Temporomandibular Disorders and Healthy Controls

open access: yesJournal of Oral Rehabilitation, EarlyView.
Using articulating foils of varying thickness, occlusal tactile acuity was compared between patients with chronic painful temporomandibular disorders (TMDp) and healthy controls. TMDp patients showed enhanced detection of thinner foils and greater perceptual sensitivity, accompanied by a more liberal decision strategy, whereas higher frequencies of ...
Iva Z. Alajbeg   +5 more
wiley   +1 more source

Ceragenins in Combination with Ivacaftor Prevent the Formation of Biofilm by Bacteria That Cause Rhinosinusitis. [PDF]

open access: yesPharmaceutics
Kaliniak S   +11 more
europepmc   +1 more source

ConformationalDynamics and Activation of Membrane-AssociatedHuman Group IVA Cytosolic Phospholipase A2 (cPLA2)

open access: green
Mac Kevin E. Braza (20901710)   +2 more
openalex   +1 more source

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