Abstract Objective To develop and internally validate a mechanistic, three‐domain framework for early classification and prediction of pre‐eclampsia (PE) using first‐trimester angiogenic, uteroplacental, and maternal vascular biomarkers. Methods In a prospective cohort of 1925 singleton pregnancies screened at 11 to 13.6 weeks, placental growth factor (
Johnatan Torres‐Torres +8 more
wiley +1 more source
A spontaneous increase in intracellular Ca2+ in metaphase II human oocytes in vitro can be prevented by drugs targeting ATP-sensitive K+ channels [PDF]
STUDY QUESTION: Could drugs targeting ATP-sensitive K+ (KATP) channels prevent any spontaneous increase in intracellular Ca2+ that may occur in human metaphase II (MII) oocytes under in vitro conditions?
Barratt, Christopher L. R. +13 more
core +6 more sources
Effect of reduced dose of triptorelin at the start of ovarian stimulation on the outcome of IVF: a randomized study [PDF]
Luca Dal Prato
openalex +1 more source
Development of a predictive model for luteal phase oocyte retrieval in poor responders undergoing natural cycle IVF [PDF]
Mara Simopoulou +12 more
openalex +1 more source
Metroplasty before IVF in women with a T‐shaped uterus: A clinical challenge
Abstract A T‐shaped uterus is a uterine malformation, which can be either congenital or acquired, potentially impairing fertility and increasing the risk of miscarriage. Diagnosis primarily relies on three‐dimensional ultrasound and hysteroscopy. Hysteroscopic metroplasty is the standard surgical intervention aimed at restoring normal uterine anatomy ...
Fabio Barra +9 more
wiley +1 more source
The impact of female obesity on the outcome of fertility treatment [PDF]
Peer reviewedPublisher ...
Abha Maheshwari +53 more
core +3 more sources
How to Prevent Early Ovulation/Luteinization During an IVF Cycle
Yoshiharu Morimoto
openalex +1 more source
Endometrial Stromal Cell Senescence: A Non‐Negligible Factor in Recurrent Pregnancy Loss
As populations age, links between female reproductive aging and infertility are increasingly evident. Cellular senescence, characterized by near‐irreversible cell‐cycle arrest and accumulation of damage, can impair tissue function. In the endometrium, aberrant senescence of endometrial stromal cells (EnSCs) may compromise receptivity, hinder embryo ...
Shuang Wu +6 more
wiley +1 more source
Clinical and Genetic Significance of Chromosomal Microarray Screening of Asymptomatic Newborns
Among 99 asymptomatic newborns with abnormal low‐resolution chromosomal microarray (LR‐CMA) screening, 70.7% harbored microduplication/microdeletions with syndromic implications. However, only a minority exhibited developmental concerns during early follow‐up, highlighting the need for cautious interpretation.
Naye Choi, Hwa Young Kim, Jung Min Ko
wiley +1 more source

