Results 81 to 90 of about 16,725 (243)

Insight into the Machinery and Applications for Understanding the Pathogen- Vector Interface [PDF]

, 2012
The availability of genome sequencing data in combination with knowledge of expressed genes via transcriptome and proteome data has greatly advanced our understanding of arthropod vectors of disease.
Barnard, Annette-Christi, Fick, Wilma, Maritz-Olivier, Christine, Nijhof, Ard Menzo, Stutzer, Christian   +4 more
core   +1 more source

Ixodes scapularis does not harbor a stable midgut microbiome [PDF]

The ISME Journal, 2017
Abstract Hard ticks of the order Ixodidae serve as vectors for numerous human pathogens, including the causative agent of Lyme Disease Borrelia burgdorferi. Tick-associated microbes can influence pathogen colonization, offering the potential to inhibit disease transmission through engineering of the tick microbiota.
Ross, Benjamin D., Hayes, Beth, Radey, Matthew C., Lee, Xia, Josek, Tanya, Bjork, Jenna, Neitzel, David, Paskewitz, Susan, Chou, Seemay, Mougous, Joseph D.   +9 more
openaire   +2 more sources

Genetic and Landscape Connectivity of Blacklegged Ticks During Range Expansion in Select States of the Midwestern USA

Ecology and Evolution, Volume 15, Issue 10, October 2025.
Blacklegged ticks (Ixodes scapularis), vectors of Lyme disease, have expanded across the Midwestern USA since the 1970s, with at least three genetically structured populations. Fine‐scale genomic and landscape analyses reveal distinct gene flow corridors and barriers, highlighting how environmental connectivity shapes tick range expansion and informing
Dahn‐young Dong, Susan M. Paskewitz, Jean I. Tsao, Sean D. Schoville   +3 more
wiley   +1 more source

Modulation of the tick gut milieu by a secreted tick protein favors Borrelia burgdorferi colonization

Nature Communications, 2017
Borrelia burgdorferi, the causative agent of Lyme disease, is transmitted by the tick Ixodes scapularis. Here, the authors show that a tick secreted protein (PIXR) modulates the tick gut microbiota and facilitates B. burgdorferi colonization.
Sukanya Narasimhan, Tim J. Schuijt, Nabil M. Abraham, Nallakkandi Rajeevan, Jeroen Coumou, Morven Graham, Andrew Robson, Ming-Jie Wu, Sirlei Daffre, Joppe W. Hovius, Erol Fikrig   +10 more
doaj   +1 more source

Isolation and multilocus sequence typing of Borrelia burgdorferi from Ixodes scapularis collected from dogs in Ontario, Canada

BMC Research Notes, 2023
Objective To identify the multilocus sequence typing (MLST) sequence types of Borrelia burgdorferi from Ixodes scapularis in Ontario, Canada. Results One hundred and eighty-five I.
Grace K. Nichol, J. Scott Weese, Katie M. Clow   +2 more
doaj   +1 more source

Caracterización de acuaporinas de garrapata como posibles antígenos protectores frente a vectores artrópodos [PDF]

, 2017
Trabajo Fin de Máster presentado por: Marinela Contreras Rojo. Máster Universitario en Investigación Básica y Aplicada en Recursos Cinegéticos.Las garrapatas son ectoparásitos hematófagos obligados que actúan como vectores de enfermedades transmitidas ...
Contreras, Marinela
core  

A Set of Rapid Diagnostic Tool for Babesia microti Infection

Journal of Clinical Laboratory Analysis, Volume 39, Issue 20, October 2025.
This study develops a cross‐priming amplification combined with vertical flow visualization (CPA‐VF) assay for rapid, low‐cost detection of Babesia microti, achieving a detection limit of 2.56 fg/reaction (equivalent to 0.000004% parasitic red blood cells) with 95.5% sensitivity and specificity compared to nested PCR.
Yanan Bai, Shangdi Zhang, Qindong Liang, Xinxin Zhang, Zeen Liu, Yuxin Ye, Jianxun Luo, Hong Yin, Chongge You, Guiquan Guan, Jinming Wang   +10 more
wiley   +1 more source

The distribution of Babesia odocoilei in Ixodes species ticks in Canada: Implications for one health surveillance

Ticks and Tick-Borne Diseases
Ixodes scapularis and Ixodes pacificus are vectors of a range of pathogens of public health significance in North America. These ticks transmit pathogens to and from wild animal reservoir host species, but also bite humans and expose them to the ...
Camille Guillot, Jérôme Pelletier, Cécile Aenishaenslin, Heather Coatsworth, Antonia Dibernardo, Jules K. Koffi, Manisha A. Kulkarni, Jean-Philippe Rocheleau, Christy Wilson, Curtis Russell, Mark P. Nelder, Jacqueline Badcock, Justin Carr, Sylvia Checkley, Katie M. Clow, Stephanie Cooper, Susan Cork, Ariane Dumas, Shaun Dergousoff, Nicoletta Faraone, Erin Fraser, Scott Graham-Derham, Alejandra Irace-Cima, Stefan Iwasawa, Emily Jenkins, Patrick A. Leighton, Roman McKay, Muhammad Morshed, Roxane Pelletier, Marion Ripoche, Kateryn Rochon, Karine Thivierge, Maarten J. Voordouw, Nicholas H. Ogden, Catherine Bouchard   +34 more
doaj   +1 more source

Detection of municipalities at-risk of Lyme disease using passive surveillance of Ixodes scapularis as an early signal: A province-specific indicator in Canada.

PLoS ONE, 2019
Lyme disease, the most commonly reported vector-borne disease in North America, is caused by the spirochete Borrelia burgdorferi sensu stricto, which is transmitted by Ixodes scapularis in eastern Canada and Ixodes pacificus in western Canada.
Salima Gasmi, Nicholas H Ogden, Marion Ripoche, Patrick A Leighton, Robbin L Lindsay, Mark P Nelder, Erin Rees, Catherine Bouchard, Linda Vrbova, Richard Rusk, Curtis Russell, Yann Pelcat, Samir Mechai, Serge-Olivier Kotchi, Jules K Koffi   +14 more
doaj   +1 more source

The fungal alkaloid Okaramine-B activates an L-glutamate-gated chloride channel from Ixodes scapularis, a tick vector of Lyme disease

International Journal for Parasitology: Drugs and Drug Resistance, 2018
A novel L-glutamate-gated anion channel (IscaGluCl1) has been cloned from the black-legged tick, Ixodes scapularis, which transmits multiple pathogens including the agents of Lyme disease and human granulocytic anaplasmosis. When mRNA encoding IscaGluCl1
Shogo Furutani, Makoto Ihara, Kristin Lees, Steven D. Buckingham, Frederick A. Partridge, Jonathan A. David, Rohit Patel, Scott Warchal, Ian R. Mellor, Kazuhiko Matsuda, David B. Sattelle   +10 more
doaj   +1 more source