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Antiplatelet Activity of J78 (2-Chloro-3-[2′-bromo, 4′-fluoro-phenyl]-amino-8-hydroxy-1,4-naphthoquinone), an Antithrombotic Agent, Is Mediated by Thromboxane (TX) A2 Receptor Blockade with TXA2 Synthase Inhibition and Suppression of Cytosolic Ca2+ Mobilization

Journal of Pharmacology and Experimental Therapeutics, 2005
We previously reported that J78 (2-chloro-3-[2'-bromo, 4'-fluoro-phenyl]-amino-8-hydroxy-1,4-naphthoquinone), a newly synthesized 1,4-naphthoquinone derivative, exhibited a potent antithrombotic effect, which might be due to antiplatelet rather than anticoagulation activity. In the present study, possible anti-platelet mechanism of J78 was investigated.
Myoung Rae Cho
exaly   +3 more sources

Inhibitory Effects of J78, a Newly Synthesized 1,4-Naphthoquinone Derivative, on Experimental Thrombosis and Platelet Aggregation

Pharmacology, 2004
Several compounds with the backbone of 1,4-naphthoquinone chemical structure have been reported to display antiplatelet and antithrombotic activities, indicating that this congener compound may be a new source in the antithrombotic drug development. In the present study, the possible antiplatelet activity and antithrombotic efficacy of J78 (2-chloro-3-[
Yong-Ri, Jin   +4 more
openaire   +2 more sources

MPEC 2023-J78 : 2023 AN6

2023
The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements. They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
openaire   +1 more source

MPEC 2025-J78 : 2025 JH2

The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements. They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
openaire   +1 more source

MPEC 2024-J78 : DAILY ORBIT UPDATE (2024 May 5)

The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements. They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
openaire   +1 more source

A novel phytopathogen Erwinia sorbitola sp. nov., isolated from the feces of ruddy shelducks

Frontiers in Cellular and Infection Microbiology, 2023
Jianguo Xu
exaly  

The quotas law for people with disabilities in Brazil: is it a guarantee of employment?

International Review of Applied Economics, 2022
Ana Cléssia Pereira Lima de Araújo
exaly  

Profit, morality and discrimination

Applied Economics, 2021
Mathieu Bunel, Elisabeth Tovar
exaly  

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