Results 51 to 60 of about 19,247,727 (260)

Intracoronary acetylcholine application as a possible probe inducing J waves in patients with early repolarization syndrome

Journal of Arrhythmia, 2017
Acetylcholine is widely used for a diagnostic provocation test of coronary spasm in patients with vasospastic angina. Acetylcholine usually induces coronary vasodilatation mediated by muscarinic receptor activation, but sometimes it evokes ...
Toru Maruyama, M.D., Ph.D., Kazumasa Fujita, M.D., Kei Irie, M.D., Shouhei Moriyama, M.D., Mitsuhiro Fukata, M.D., Ph.D.   +4 more
doaj   +1 more source

Precursor of pair-density wave in doping Kitaev spin liquid on the honeycomb lattice

npj Quantum Materials, 2021
We study the effects of doping the Kitaev model on the honeycomb lattice where the spins interact via the bond-directional interaction J K, which is known to have a quantum spin liquid as its exact ground state.
Cheng Peng, Yi-Fan Jiang, Thomas P. Devereaux, Hong-Chen Jiang   +3 more
doaj   +1 more source

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li, Dong‐Lin Liang, Li‐Ping Gao, Wei‐Wei Zhang, Wei Zhou, A. Ruhan, Bing Xu, Run‐Dong Cao, Kang Xiao, Cao Chen, Qi Shi, Xiao‐Ping Dong   +11 more
wiley   +1 more source

Prediction of Shock Wave Velocity Temporal Evolution Induced by Ms-Ns Combined Pulse Laser Based on Attention-LSTM

Photonics
This study systematically examined shock wave velocity induced by millisecond–nanosecond combined-pulse laser (ms–ns CPL) at a fixed ns laser energy density of 6 J/cm2, exploring the effects of varying pulse delays of 0 to 3 ms and ms laser energy ...
Jingyi Li, Rongfan Liang, Junjie Liu, Jingdong Sun   +3 more
doaj   +1 more source

Type-II t-J model in superconducting nickelate Nd_{1−x}Sr_{x}NiO_{2}

Physical Review Research, 2020
The recent observation of superconductivity at relatively high temperatures in hole-doped NdNiO_{2} has generated considerable interest, particularly due to its similarity with the infinite layer cuprates.
Ya-Hui Zhang, Ashvin Vishwanath
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

ECG Markers of Positive Drug Challenge With Ajmaline in Patients With Brugada Syndrome

Annals of Noninvasive Electrocardiology
Background Ajmaline challenge (AC) is used for diagnosing suspected Brugada syndrome (BS) in patients with unexplained syncope, survived cardiac arrest, or for family screening.
Erol Tülümen, Mathieu Kruska, Sara Wuerfel, Maximilian Kohl, Volker Liebe, Ibrahim Akin, Juergen Kuschyk, Daniel Duerschmied, Martin Borggrefe, Boris Rudic   +9 more
doaj   +1 more source

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay, Cassandre Landes‐Château, Lydiane Mondot, Mikael Cohen, Margherita Popolo, Jérôme de Seze, Bertrand Bourre, Françoise Durand‐Dubief, Olivier Casez, Orhun H. Kantarci, Aksel Siva, Stephanie Baillif, Darin T. Okuda, Letizia Leocani   +13 more
wiley   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source