Results 161 to 170 of about 12,796 (256)

SURMOUNT‐REAL UK: A Pragmatic Randomized Clinical Trial to Assess the Effectiveness of Tirzepatide in Adults With Obesity

Obesity, EarlyView.
ABSTRACT Objective SURMOUNT‐REAL UK will evaluate the effectiveness of tirzepatide when offered in addition to standard‐of‐care (SoC) in adults with Class I obesity (BMI ≥ 30 and ≤ 34.9 kg/m2) and without diabetes in a UK primary care setting. Methods A 5‐year, phase 4, multicenter, open‐label, pragmatic randomized clinical trial is enabled through ...
Martin K. Rutter, Julie Mount, J. Martin Gibson, Joanne Webb, Cheryl Marler, Catherine Reed, Mugdha Gore, Wenyu Ye, Elisa Gomez Valderas, John Wilding, Naveed Sattar, Melanie J. Davies, Kamlesh Khunti, Richard Haynes, Rachel L. Batterham   +14 more
wiley   +1 more source

Genetic diversity and architectural dynamics of soybean centromeres. [PDF]

Genome Biol
Huang Y, Guan E, Song S, Koo DH, Schmidt MA, Su H, Chen C, Zhang J.   +7 more
europepmc   +1 more source

The Diagnostic Performance of Afirma Genomic Sequencing Classifier in Black and Hispanic Patients With Indeterminate Thyroid Nodules

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective About 20% of thyroid nodules detected on ultrasound are cytologically indeterminate (Bethesda categories III and IV), but the rate of malignancy of these nodules is less than 36%. The ability of Afirma Genomic Sequencing Classifier (GSC) to further risk‐stratify indeterminate thyroid nodules among Black and Hispanic patients is ...
Peter J. Attia, Sree Chinta, Joseph Celidonio, John Sebastian De Armas, Evelyne Kalyoussef, Dylan F. Roden   +5 more
wiley   +1 more source

The Paediatric Intensive Care Adaptive Platform Trial (PIVOTAL): Turning Pediatric Critical Care Practice Into Clinical Research. [PDF]

Pediatr Crit Care Med
Peters MJ, Mouncey P, Mason A, Shahid T, Ramnarayan P, Ray S, Brown K, Chang I, Gould DW, Harrison D, and the Paediatric Intensive Care Adaptive Platform Trial (PIVOTAL) investigators for Paediatric Critical Care Society Study Group (PCCS-SG).   +10 more
europepmc   +1 more source

Broad support for lethal control of wild deer among subscribers of nature organisations in England and Wales

People and Nature, EarlyView.
Abstract Wild deer populations are increasing across the northern hemisphere, posing challenges to the environment and people. Deer impacts can be managed using lethal and non‐lethal practices, but research suggests lethal control receives mixed support.
Elena Cini, Rebecca Spake, Louise McMillan, Amy Gresham, Graeme Shannon, Felix Eigenbrod, Christopher P. Nichols, Paul Orsi, Alastair I. Ward, Freya A. V. St John   +9 more
wiley   +1 more source

OpenMCT: an open-source DC motor control educational kit. [PDF]

HardwareX
Von Chong A, Vargas S, Duhé JF, Cárdenas D.   +3 more
europepmc   +1 more source

Clinical interpretation of cardiac troponin in athletes: From endurance exercise to exertional injury

PM&R, EarlyView.
Abstract Exertional heat illness (EHI) and exertional rhabdomyolysis (ER) are increasingly recognized causes of morbidity in competitive and tactical athletes. Cardiac troponin (cTn) elevation, traditionally viewed as a marker of myocardial necrosis, may also be seen in these settings and can create significant diagnostic and prognostic uncertainty ...
John‐Henry L. Dean, Jeffrey C. Leggit, M. Alaric Franzos   +2 more
wiley   +1 more source

Simulation-Based Evaluation of a Large Language Model-Enabled Clinical Decision Support Platform in Oncology. [PDF]

JCO Clin Cancer Inform
Lajmi N, Patel M, Obery G, Dorge A, Sharma A, Halligan J, Lo E.   +6 more
europepmc   +1 more source

Agricultural and environmental drivers of variation in the composition of food crops: A scoping review

PLANTS, PEOPLE, PLANET, EarlyView.
Agricultural management and environmental conditions influence the biochemical composition of food crops; however, the specific drivers of this variation remain insufficiently understood, despite their importance for climate change adaptation and human health.
Kat Morgan, Teresa Warne, Sahar Toulabi, Fangzhou Li, Amanda Birnbaum, Shawn Ehlers Cheang, Cheng‐Yu Weng, Warangkana Srichamnong, Simab Kanwal, Linda Nana Esi Aduku, Charles Apprey, Kifle Habte Balcha, Herman Erick Lutterodt, Madeleine McGuinness, Bo Wallace, Layla Manoochehri, Alex C. McAlvay, Mary Ann Nunoo, Pearl Boamah Agyekum, Reginald A. Annan, Charlene van Buiten, Mariana Barboza, John de la Parra, Selena Ahmed, Sarah Brinkley   +24 more
wiley   +1 more source

Surprising Variability in Tryptamine Profiles of <i>Psilocybe cubensis</i> Fruiting Bodies: Inter- and Intra-Strain Differences Across 14 Strains Cultivated Under Controlled Conditions. [PDF]

J Fungi (Basel)
Sharchaton A, Parsha S, Azerrad SP, Dekel Y, Rabah N, Páleníček T, Kurzbaum E.   +6 more
europepmc   +1 more source