Results 181 to 190 of about 919,385 (310)

A proof of Jackson’s theorem [PDF]

open access: yesBulletin of the American Mathematical Society, 1969
Bojanic, R., DeVore, R.
openaire   +2 more sources

Machine Learning‐Enhanced Ultrasensitive Immuno‐CRISPR Array Facilitates Early Diagnosis of Alzheimer's Disease by Detecting Multiple Plasma Biomarkers

open access: yesAdvanced Science, EarlyView.
This work presents a CRISPR‐based, ultrasensitive multiplex protein detection array capable of simultaneously analyzing six plasma biomarkers associated with Alzheimer's disease (AD). By integrating antibody‐mediated signal transduction, recombinase polymerase amplification, and spatially encoded CRISPR‐Cas12a, the system achieves detection sensitivity
Liding Zhang   +9 more
wiley   +1 more source

Ian T. Jackson

open access: yesIndian Journal of Plastic Surgery, 2020
Surajit Bhattacharya
doaj   +1 more source

RNF138‐Mediated Ubiquitination and Degradation of NS5 Restricts Tick‐Borne Encephalitis Virus Infection

open access: yesAdvanced Science, EarlyView.
Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun   +6 more
wiley   +1 more source

A case report of an interventricular septal hematoma presenting as a STEMI post-pacemaker implantation

open access: yesHeartRhythm Case Reports
Diva Maraj, MD   +6 more
doaj   +1 more source

The oxygen paradox in retinopathy of prematurity: could fetal hemoglobin be the key? [PDF]

open access: yesFront Pediatr
Jackson MTA   +4 more
europepmc   +1 more source

Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing

open access: yesAdvanced Science, EarlyView.
Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan   +13 more
wiley   +1 more source

Advances in Natural Products and Their Biological Activities. [PDF]

open access: yesMolecules
de Menezes IRA   +6 more
europepmc   +1 more source

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