Results 71 to 80 of about 1,195,616 (312)

Genetic context modulates aging and degeneration in the murine retina

Molecular Neurodegeneration
Background Age is the principal risk factor for neurodegeneration in both the retina and brain. The retina and brain share many biological properties; thus, insights into retinal aging and degeneration may shed light onto similar processes in the brain ...
Olivia J. Marola, Michael MacLean, Travis L. Cossette, Cory A. Diemler, Amanda A. Hewes, Alaina M. Reagan, Jonathan Nyandu Kanyinda, Daniel A. Skelly, Gareth R. Howell   +8 more
doaj   +1 more source

1930 Appointment Diary of Mayor William Jackson

, 2018
This 1930 appointment diary was used by Mayor William Trayton Jackson to manage his schedule. Jackson was born in 1876, mayor of Toledo, Ohio from 1928 to 1931, and died in 1933 and is buried in Woodlawn ...
Jackson, William Trayton
core  

A Retinal Matrix Stiffening Model Reveals FAK‐Dependent Mechanotransduction in Pericytes Underlies Vascular Destabilization

Advanced Materials, EarlyView.
In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren, Alex Wu, Lucas Ramirez, Yaqing Huang, Connor Amelung, Sophia Saxonhouse, Sharon Gerecht   +6 more
wiley   +1 more source

Ron Jackson

, 2007
"VX64635 Gnr Ron Jackson 2/4th Aust Field Regt 8th Division Darwin 1942 - 43 Railway Hill Myilly Point".VX64635 Gunner Ron Jackson. 2/4th Australian Field Regiment, 8th Division. Darwin 1942 - 43.
Jackson, Ron
core  

A Noninvasive Approach to Study Localized Forces in 3D Epithelia

Advanced Materials, EarlyView.
Epithelial morphogenesis depends on dynamic mechanical coupling between adhesion complexes and the cytoskeleton, yet its regulation in polarized 3D tissues remains elusive. We developed a noninvasive strategy using cell‐like elastic microbeads to quantify local forces in intact epithelia.
Niels Gouirand, Muhamet Ibrahimi, Claire Valotteau, Brice Lecouffe, André Le Bivic, Dominique Massey‐Harroche, Felix Rico, Matthias Merkel, Delphine Delacour, Elsa Bazellières   +9 more
wiley   +1 more source

Genomic data analysis workflows for tumors from patient-derived xenografts (PDXs): challenges and guidelines

BMC Medical Genomics, 2019
Background Patient-derived xenograft (PDX) models are in vivo models of human cancer that have been used for translational cancer research and therapy selection for individual patients.
Xing Yi Woo, Anuj Srivastava, Joel H. Graber, Vinod Yadav, Vishal Kumar Sarsani, Al Simons, Glen Beane, Stephen Grubb, Guruprasad Ananda, Rangjiao Liu, Grace Stafford, Jeffrey H. Chuang, Susan D. Airhart, R. Krishna Murthy Karuturi, Joshy George, Carol J. Bult   +15 more
doaj   +1 more source

Jean Jackson in her house

, 1969
Jean Jackson in her house, with Alicia Castillo.
Jackson, Jean
core  

Gonadotropin‐Inhibitory Hormone (GnIH) and Its Receptor GPR147 Mediates Acute Stress‐Induced Activation of the Locus Coeruleus‐SAM Axis

Advanced Science, EarlyView.
ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang, Hongyu Zhu, Wenqi Wang, Bingqian Shen, Yuanyuan Xin, Xingxing Song, Xuanyi Lu, Lixuan Li, Siting Chen, Xiaochen Zhang, Jialing Zeng, Haodong Zheng, Jianlong Lao, Ke Peng, Yixian Wei, Jiaming Zheng, Chuanhuo Hu, Xiaoye Wang, Xun Li   +18 more
wiley   +1 more source

Terrorismo: un enfoque crítico

Relaciones Internacionales, 2015
Review-essay de: • JACKSON, Richard, et al., Terrorism. A Critical Introduction, Palgrave Macmillian Nueva York, 2011, ps. 332. • JACKSON, Richard y SINCLAIR, Samuel Justin (ed.), Contemporary Debates on Terrorism, Routledge, Nueva York, 2012, ps. 218.
Alice MARTINI
doaj  

Oral History Interview with Billy Jackson, June 17, 2005

, 2005
The National Museum of the Pacific War presents on oral interview with Billy Jackson. Jackson joined the Navy in August, 1944 and was assigned aboard USS Fergus (AP-82).
Jackson, Billy
core