Results 181 to 190 of about 1,169,585 (308)

Dr. Chevalier Jackson [PDF]

The Journal of Laryngology & Otology, 1958
openaire   +2 more sources

ATL2 Recruits TRAK1 to Promote Mitochondrial Transport at ER–Mitochondria Contact Sites

Advanced Science, EarlyView.
ABSTRACT Mitochondrial transport and distribution are crucial for cellular homeostasis, yet whether and how they are regulated by endoplasmic reticulum (ER)–mitochondria contact sites remains unclear. Here, we demonstrate that the ER protein atlastin‐2 (ATL2) orchestrates mitochondrial transport and distribution by promoting assembly of the transport ...
Yiru Cheng, Peiyuan Chai, Xiayuhe Pei, Yiwen Chen, Xiaoshuai Huang, Bei Liu, Yiqian Wu, Junlin Teng, Pengli Zheng, Jianguo Chen   +9 more
wiley   +1 more source

A case report of an interventricular septal hematoma presenting as a STEMI post-pacemaker implantation

HeartRhythm Case Reports
Diva Maraj, MD, Garima Gandotra, MD, Muhammad Ahmad Qureshi, MD, Iman El-Feki, MD, Omair Ahmed, MD, Hussein Othman, MD, Mumtaz Memon, MD   +6 more
doaj   +1 more source

Targeting Hippocampal PTEN Suppresses Ferroptosis and Rescues Cognitive Decline in Alzheimer's Disease via Dual AKT/GSK3β/Nrf2 and AKT/STAT3 Axes

Advanced Science, EarlyView.
PTEN knockdown activates AKT phosphorylation, promoting Nrf2 nuclear translocation and STAT3 activation, which upregulates GPX4 and antioxidant enzymes HO‐1, SOD1, SOD2, and NQO1. These coordinated changes reduce lipid peroxidation and ROS, inhibit ferroptosis, and ultimately ameliorate cognitive impairment in APP/PS1 transgenic mice, highlighting a ...
Da‐Wei Wang, Meng‐Meng Liu, Yu‐Chen Zhao, Jia‐Yi Li, Wen Li, Xin Yu   +5 more
wiley   +1 more source

Classifying Foot Arch Morphologies Using High-Sensitivity Pressure Mat Technology: Prevalence Estimates and Associations With Pain, Activity Limitations, and Patient Characteristics in a Community-Based Adult Sample. [PDF]

Cureus
Jackson JB, Davis HT, Das Gupta R, Delahunty N, Dias T, Ventresca HC, Gonzalez TA, Alberg AJ.   +7 more
europepmc   +1 more source

Sonoselective Transfection of Glioma Endothelium

Advanced Science, EarlyView.
Delivering non‐viral, gene‐bearing nanoparticles with thiol‐decorated surfaces to gliomas with focused ultrasound yields transfection tropism for endothelial cells. From this platform, “sonoselective” transfection of glioma endothelium is achieved via incorporation of an endothelial cell‐specific promoter.
Anna C. Debski, Catherine M. Gorick, Victoria R. Breza, Jackson Tirrell, Krishan Perumal, Katherine M. Nowak, Ji Song, Natasha D. Sheybani, Richard J. Price   +8 more
wiley   +1 more source

Rapid Quantitative Determination of Enantiomeric Excess by Vibrational Circular Dichroism Using Noise Based Spectral Selection. [PDF]

Chirality
Jackson AM, Bows JR, Nash GR.
europepmc   +1 more source

Maternal Exercise Rescues Embryonic Osteogenesis Impaired due to POLG Mutation Through a Potential Apelin‐ATF4 Axis

Advanced Science, EarlyView.
Maternal exercise (ME) increases apelin abundance across maternal and fetal tissues and is associated with improved fetal osteogenesis under POLG mutation‐induced mitochondrial dysfunction. Apelin‐APJ signaling is linked to enhanced mitochondrial function, Akt phosphorylation, and ATF4‐RUNX2 association, supporting coordinated fetal bone remodeling ...
Song Ah Chae, Ryan C. Riddle, Zhihua Jiang, Chaeyoung Shin, Min Du, Jun Seok Son   +5 more
wiley   +1 more source

Mechanisms Underlying an Enhanced Navigation-Based Intervention to Improve Timely Adjuvant Therapy: A Secondary Analysis of the NDURE Randomized Clinical Trial. [PDF]

JAMA Otolaryngol Head Neck Surg
Elhage MN, Kistner-Griffin E, DeMass R, Chera BS, Sterba KR, Halbert CH, Hill EG, Nussenbaum B, Alberg AJ, Nguyen MT, Newman JG, Albergotti WG, Kejner AE, Skoner JM, Adilbay D, Bobian M, Harper JL, Kaczmar J, Zimmerman SA, Stewart S, McLeod T, Sandulache VC, Hermandez DJ, Jackson RS, Puram SV, Kahmke R, Osazuwa-Peters N, Jackson G, Wasp GT, Yom SS, Graboyes EM.   +30 more
europepmc   +1 more source

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

Advanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang, Bing‐Jie Tang, Jia‐Yi Li, Shu‐Lan Xie, Shumin Duan, Junping Chen, Shengmei Zhu, Zhen‐Zhong Xu   +7 more
wiley   +1 more source