Results 21 to 30 of about 2,892,244 (294)
Background: Chest tubes are used in every case of coronary artery bypass grafting (CABG) to evacuate shed blood from around the heart and lungs. This study was designed to assess the effective of Jackson-Pratt drain in compare with conventional chest ...
Mohsen Mirmohammad-Sadeghi +2 more
doaj +1 more source
Cultivation of common bacterial species and strains from human skin, oral, and gut microbiota
Background Genomics-driven discoveries of microbial species have provided extraordinary insights into the biodiversity of human microbiota. In addition, a significant portion of genetic variation between microbiota exists at the subspecies, or strain ...
Elizabeth Fleming +14 more
doaj +1 more source
Chevalier Jackson, M.D. (1865-1958): Il ne se repose jamais. [PDF]
In the final year of the American Civil War, 1865, Chevalier Jackson was born on the 4th of November just outside Pittsburgh, Pennsylvania. The eldest of three sons of a poor, livestock-raising family, Jackson was raised in a period of social and ...
Cowan, MD, Scott W. +3 more
core +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
National Newspaper Analysis of the Press Coverage of Jesse Jackson\u27s 1984 Presidential Campaign: The Confirmation of the Candidate [PDF]
Jesse Jackson\u27s 1984 and 1988 presidential campaigns have motivated thousands of citizens throughout America to take a more active role in politics. The 1984 campaign witnessed many previously unregistered Americans actively participating in Jackson ...
Baukus, Robert A. +2 more
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Equivalence between various Shape Preserving Approximations of periodic functions
We show that the validity of Jackson-type estimates in comonotone and coconvex approximations of continuous $2\pi$-periodic functions by trigonometric polynomials is equivalent to the validity of the corresponding estimates of approximation by continuous
D. Leviatan, O.V. Motorna, I.O. Shevchuk
doaj +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Comparação da composição corporal utilizando dobras cutâneas e bioimpedância em adultos jovens
A avaliação da composição corporal é de grande importância para que profissionais da área da saúde possam obter informações individuais de qualidade, e assim propor as melhores estratégias para a obtenção dos objetivos.
Jean Carlos Pancine de Oliveira +2 more
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