Results 41 to 50 of about 2,892,244 (294)

Inhibition of insulin‐like growth factor 2 mRNA‐binding protein 1 sensitizes colorectal cancer cells to chemotherapeutics

open access: yesFASEB BioAdvances, 2022
Although colorectal cancer (CRC) treatment has seen a remarkable improvement in the recent years, many patients will develop metastasis due to the resistance of cancer cells to chemotherapeutics.
Nicole Betson   +7 more
doaj   +1 more source

Probiotics in gastroenteritis in children: A systematic review

open access: yesIMC Journal of Medical Science, 2023
Background and objectives: Gastroenteritis is the second leading cause of death among children worldwide. It is a preventable and treatable disease, yet it affects 3 to 5 million children and is the cause of approximately 10% of hospitalizations globally.
Elizabeth A.K. Jones   +5 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Quality management of microfilming projects

open access: yesLiber Quarterly: The Journal of European Research Libraries, 2003
I would like to tell you something about my work as quality manager microfilming and about the high quality standards for substitute microfilming we apply within the Dutch preservation programme Metamorfoze. Let me start with going back in time a bit. To
Hans van Dormolen
doaj   +1 more source

Jefferson Jackson Day Dinner Speech [PDF]

open access: yes, 1984
Speech for the Jefferson Jackson Day Dinner, Ames, IA, October, 13, 1984. Includes handwritten notes and diacritic marks.https://ir.lawnet.fordham.edu/vice_presidential_campaign_speeches_1984/1048/thumbnail ...
Ferraro, Geraldine
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Extensor Tendon Reconstruction in Vaughan–Jackson Syndrome: Surgical Technique and a Case Illustration

open access: yesApollo Medicine
Background and Aims: Vaughan–Jackson syndrome, a complication of rheumatoid arthritis, presents with extensor tendon rupture, dorsal tenosynovitis, distal radioulnar synovitis, dorsal subluxation of the distal ulna, and wrist arthritis.
J. Terrence Jose Jerome   +1 more
doaj   +1 more source

Large deviations of a modified Jackson network: stability and rough asymptotics

open access: yes, 2005
Consider a modified, stable, two node Jackson network where server 2 helps server 1 when server 2 is idle. The probability of a large deviation of the number of customers at node one can be calculated using the flat boundary theory of Schwartz and Weiss [
Foley, Robert D., McDonald, David R.
core   +2 more sources

Three Poems [PDF]

open access: yes, 2018
Poetry by Renée Jackson ...
Jackson-Harper, Renée
core   +2 more sources

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