Results 71 to 80 of about 1,485 (264)

Neurotransmitter‐Defined Degeneration Patterns in Sporadic and C9orf72‐Associated Amyotrophic Lateral Sclerosis: Predilection to GABAergic, Serotonergic, Opioid, Glutamatergic, Endocannabinoid, and Microglial Systems—Implications for Therapy Development

open access: yesAnnals of Neurology, EarlyView.
Objective Amyotrophic lateral sclerosis (ALS) has a markedly distinctive clinical and neuroradiological signature, with the preferential involvement of specific brain networks and the apparent sparing of others. The molecular underpinnings of the strikingly selective anatomical vulnerability have not been fully elucidated to date despite the potential ...
Marlene Tahedl   +10 more
wiley   +1 more source

GENERALIZED EXPLICIT DESCENT AND ITS APPLICATION TO CURVES OF GENUS 3

open access: yesForum of Mathematics, Sigma, 2016
We introduce a common generalization of essentially all known methods for explicit computation of Selmer groups, which are used to bound the ranks of abelian varieties over global fields.
NILS BRUIN, BJORN POONEN, MICHAEL STOLL
doaj   +1 more source

Artificial Neural Network Driven Computational Modeling of Naegleria fowleri Epidemics Using Variational Optimization

open access: yesAdvanced Physics Research, EarlyView.
ABSTRACT This study presents a mathematical framework to analyze the transmission dynamics of an amoeba‐induced central nervous system infection. The population is divided into compartments including susceptible, exposed, infected, quarantined, hospitalized, recovered, protected, and deceased.
Wakeel Ahmed   +3 more
wiley   +1 more source

A Diagonally Updated Limited-Memory Quasi-Newton Method for the Weighted Density Approximation

open access: yesComputation, 2017
We propose a limited-memory quasi-Newton method using the bad Broyden update and apply it to the nonlinear equations that must be solved to determine the effective Fermi momentum in the weighted density approximation for the exchange energy density ...
Matthew Chan   +3 more
doaj   +1 more source

On the Jacobian of the Klein curve [PDF]

open access: yesProceedings of the American Mathematical Society, 1994
Its is known that the Jacobian J of the Klein curve is isogenous to E
openaire   +1 more source

Model‐Enabled Knowledge Transfer Across Cell Lines, Culture Scales and Conditions

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Mechanistic models are central to quantitative understanding and optimization of Chinese hamster ovary (CHO) cell culture processes, but their utility is often restricted by parameter sets calibrated for specific cell lines, scales, or operating conditions.
Luxi Yu   +2 more
wiley   +1 more source

Revisiting Fisher's n‐D statistical vision: From algebraic abstraction to modern visualization

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract We revisit early foundational results in mathematical statistics derived by Ronald A. Fisher. They involve sampling distributions of statistics calculated from independent and identically distributed Normal observations, namely the root mean square deviation; the mean absolute deviation, conditional on already knowing the value of the root ...
James A. Hanley
wiley   +1 more source

An Accelerated Discrete Ordinate Method (ADOM) Developed for Scalar Radiative Transfer by Merging Adjacent Clear‐Sky Atmospheric Layers: Forward and Jacobians Derivation

open access: yesJournal of Advances in Modeling Earth Systems
In this study, an Accelerated Discrete Ordinate Method (ADOM) is proposed to enhance the computational efficiency of multi‐layer radiative transfer (RT) simulations while maintaining a high accuracy.
Yi‐Ning Shi, Fuzhong Weng
doaj   +1 more source

Front Propagation Through a Perforated Wall

open access: yesCommunications on Pure and Applied Mathematics, EarlyView.
ABSTRACT We consider a bistable reaction– diffusion equation ut=Δu+f(u)$u_t=\Delta u +f(u)$ on RN${\mathbb {R}}^N$ in the presence of an obstacle K$K$, which is a wall of infinite span with many holes. More precisely, K$K$ is a closed subset of RN${\mathbb {R}}^N$ with smooth boundary such that its projection onto the x1$x_1$‐axis is bounded and that ...
Henri Berestycki   +2 more
wiley   +1 more source

Coupling Fluid Neutrals to Gyrokinetic Plasma Dynamics for Edge and SOL Turbulence Simulations

open access: yesContributions to Plasma Physics, EarlyView.
ABSTRACT Accurate modeling of turbulent transport in magnetic confinement fusion devices requires extending first‐principles gyrokinetic simulations from the core to the edge and scrape‐off layer (SOL), where additional physics—particularly plasma–neutrals interactions—must be included.
Sabine Ogier‐Collin   +3 more
wiley   +1 more source

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