Results 41 to 50 of about 85,063 (287)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Abrocitinib 100 mg Once Daily for Moderate-to-Severe Atopic Dermatitis: A Review of Efficacy and Safety, and Expert Opinion on Use in Clinical Practice

Dermatology and Therapy, 2023
Abrocitinib is a Janus kinase (JAK) 1-selective inhibitor approved for the treatment of moderate-to-severe atopic dermatitis (AD). Although specific dose recommendations for abrocitinib vary across regional product labels, abrocitinib 100 mg once daily ...
Melinda J. Gooderham, Andrew E. Pink, Eric L. Simpson, Jonathan I. Silverberg, Erman Güler, Melissa Watkins   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Investigations on 3D reconstruction of bones in surgery using a handheld trinocular camera system [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Knee arthroplasty benefits significantly from computer-assisted navigation, which improves the accuracy of prosthesis placement. However, current methods require invasive optical locators to track the position of the knee, which carries risks such as ...
A. Schierbaum, T. Neiss-Theuerkauff, T. Luhmann, F. Wallhoff, T. Sieberth   +4 more
doaj   +1 more source

PRECISE LASER-BASED OPTICAL 3D MEASUREMENT OF WELDING SEAMS UNDER WATER [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2015
This paper deals with the development of a measuring procedure and an experimental set-up (stereo camera system in combination with a projecting line laser and a positioning unit) which are intended to detect the surface topography, particularly of welds,
T. Ekkel, J. Schmik, T. Luhmann, H. Hastedt   +3 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Evaluation of head-tracked binaural auralizations of speech signals generated with a virtual artificial head in anechoic and classroom environments

Acta Acustica, 2021
In order to realize binaural auralizations with head tracking, BRIRs of individual listeners are needed for different head orientations. In this contribution, a filter-and-sum beamformer, referred to as virtual artificial head (VAH), was used to ...
Fallahi Mina, Hansen Martin, Doclo Simon, van de Par Steven, Püschel Dirk, Blau Matthias   +5 more
doaj   +1 more source

Jade magique et Jade sombre

Impressions d’Extrême-Orient, 2014
HONG LOU MENG – trois syllabes quasiment magiques a l'oreille et au cœur des lettres et des lecteurs chinois ! Erudit mandarin ou lecteur ordinaire, nul n'y est indifferent, et l'on nous dit que tel lettre ne pouvait vivre sans avoir toujours a portee de la main un exemplaire de ce « Songe aux pavillons rouges », que tel autre passa sa vie a recenser ...
openaire   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Once-Daily Abrocitinib for the Treatment of Moderate-to-Severe Atopic Dermatitis in Adults and Adolescents Aged 12 Years and Over: A Short Review of Current Clinical Perspectives

Therapeutics and Clinical Risk Management, 2022
Elena Niculet,1,2,* Carmen Bobeica,1 Ioana Anca Stefanopol,1,3 Ana Maria Pelin,4,* Alexandru Nechifor,2,5,* Cristian Onisor,1,* Alin Laurentiu Tatu2,4,5 1Department of Morphological and Functional Sciences, Faculty of Medicine and ...
Niculet E, Bobeica C, Stefanopol IA, Pelin AM, Nechifor A, Onisor C, Tatu AL   +6 more
doaj