Results 141 to 150 of about 8,938 (293)

European S2k guidelines on management of autoimmune blistering diseases in children and adolescents

open access: yesJournal of the European Academy of Dermatology and Venereology, Volume 40, Issue 7, Page 1137-1161, July 2026.
Autoimmune blistering disorders (AIBDs) in children are rare, challenging to diagnose and treat and often require immunosuppressants. Until now, no paediatric care guidelines existed. The EADV Task Force for AIBDs has developed the consensus‐based recommendations, enabling physicians to adopt a uniform, tailored treatment strategy to improve outcomes ...
A. Nanda   +31 more
wiley   +1 more source

Jaguar manifestation in Mesoamerica and Peru

open access: yes, 2014
This paper examines the different manifestations of the jaguar and its relationship with four different cultures: Olmec, Teotihuacan, Maya and Chavin de Huantar.
Amandine Dorian Castex
core  

Pegargiminase Suppresses the Fanconi Anemia Pathway and Promotes Melphalan‐Induced DNA Double‐Strand Breaks in Uveal Melanoma

open access: yesPigment Cell &Melanoma Research, Volume 39, Issue 4, July 2026.
ADI‐PEG20 enhances melphalan‐induced DNA DSBs in UM cells. We describe potentiation of DNA DSBs in UM cell lines upon treatment with ADI‐PEG20 and melphalan (92.1 cells with STRIDE by intoDNA). ADI‐PEG20 suppresses multiple members of the FA pathway—a known resistance mechanism for melphalan—providing a rationale for exploring this drug combination in ...
Iuliia Pavlyk   +10 more
wiley   +1 more source

The Intricate Mechanism of Nitric Oxide Synthase

open access: yesJournal of Computational Chemistry, Volume 47, Issue 17, 30 June 2026.
The mechanism for NO formation by Nitric Oxide Synthase (NOS) has been studied using accurate DFT methods. A long‐range electron transfer from the cofactor H4B leads to formation of H2O2. ABSTRACT The biological formation of NO is performed by nitric oxide synthase.
Per E. M. Siegbahn
wiley   +1 more source

Naturally Taught [PDF]

open access: yes
Jeremy Siegel (Nuclear Jaguar)Naturally Taught, 2024 Fandom: Video Game Music Music, Photo ManipulationN/A, Variable dimensions Collection of the artist Rating: General Audiences Tags: Music, video games, hip-hop, funk, electronic, retro, Sonic the ...
Jeremy Siegel (Nuclear Jaguar)
core  

Exercise Training Stimulates the Release of Glutathione Peroxidase 1 (GPX1)‐Enriched Extracellular Vesicles That Promote Angiogenesis

open access: yesThe FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Exercise Training Stimulates the Release of Glutathione Peroxidase 1 (GPX1)‐Enriched Extracellular Vesicles that Promote Angiogenesis. The results from this study suggest that EVs isolated from blood immediately after the last bout of endurance exercise training (ExerV) are enriched in antioxidants. ExerVs stimulate vascular growth both in vitro and in 
Alexander M. Fliflet   +23 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1556-1590, June 2026.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

ESTUDIO PRELIMINAR SOBRE EL PROBLEMA DE LA DEPREDACIÓN DE GANADO POR JAGUARES (PANTHERA ONCA) Y PUMAS (PUMA CONCOLOR) EN EL PARQUE NACIONAL PORTOBELO, PROVINCIA DE COLÓN, PANAMÁ

open access: yesTecnociencia, 2008
     Este estudio permitió confirmar que existe un conflicto entre los ganaderos del área y los jaguares y pumas del Parque Nacional Portobelo que no había sido documentado anteriormente.
Ricardo S. Moreno R., Melva H. Olmos Y.
doaj  

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