Results 81 to 90 of about 958,890 (240)

Vía JAK-STAT e inhibidores JAK

open access: yesDermatología Argentina, 2022
La vía JAK-STAT (Janus Kinasas) es una cadena de traducción de señales intracelulares, que se activa a través de receptores de citoquinas I y II. Mediante esta vía, varias moléculas de importancia en dermatología ejercen sus efectos: IL2, IL4, IL7, IL5, IL6, IL9, IL12, IL13, IL15, IL21, IL23, INFa e INFb, entre otras.
openaire   +1 more source

TRANSLATING MEDICAL TEXTS FOR LEGAL PURPOSES: A GROWING CHALLENGE FOR COURT TRANSLATORS AND INTERPRETERS [PDF]

open access: yes, 2012
Przekład tekstów medycznych obejmuje cały szereg różnego typu tekstów, takich jak wypisy szpitalne, epikryzy, artykuły naukowe w czasopismach medycznych, ulotki informacyjne dla pacjenta (PILs) czy też wskazówki dotyczące stosowania leku (IFU).
KOŚCIAŁKOWSKA-OKOŃSKA, Ewa
core   +2 more sources

JAK–STAT Signaling as a Target for Inflammatory and Autoimmune Diseases: Current and Future Prospects

open access: yesDrugs, 2017
The Janus kinase/signal transduction and activator of transcription (JAK–STAT) signaling pathway is implicated in the pathogenesis of inflammatory and autoimmune diseases including rheumatoid arthritis, psoriasis, and inflammatory bowel disease.
Shubhasree Banerjee   +4 more
semanticscholar   +1 more source

JAK: Not Just Another Kinase.

open access: yesMolecular Cancer Therapeutics, 2022
The Janus kinase/signal transducer and activator of transcription (JAK/STAT) axis is implicated in cancer, inflammation, and immunity.Numerous cytokines/growth factors affect JAK/STAT signaling.
Ruchi P Agashe, S. Lippman, R. Kurzrock
semanticscholar   +1 more source

Eski İstanbul'un yaşayan tadı [PDF]

open access: yes, 1988
Taha Toros Arşivi, Dosya No: 112-Lokantalarİstanbul Kalkınma Ajansı (TR10/14/YEN/0033) İstanbul Development Agency (TR10/14/YEN ...
Deleon, Jak
core  

The computability path ordering [PDF]

open access: yes, 2015
This paper aims at carrying out termination proofs for simply typed higher-order calculi automatically by using ordering comparisons. To this end, we introduce the computability path ordering (CPO), a recursive relation on terms obtained by lifting a ...
Blanqui, Frédéric   +2 more
core   +7 more sources

The molecular details of cytokine signaling via the JAK/STAT pathway

open access: yesProtein Science, 2018
More than 50 cytokines signal via the JAK/STAT pathway to orchestrate hematopoiesis, induce inflammation and control the immune response. Cytokines are secreted glycoproteins that act as intercellular messengers, inducing proliferation, differentiation ...
Rhiannon Morris, N. Kershaw, J. Babon
semanticscholar   +1 more source

Waiting for JAK inhibitor safety data

open access: yesRMD Open, 2022
The US Food and Drug Administration (FDA) has recently added a new ‘black box warning’ on all currently approved Janus kinase (JAK) inhibitors indicated for the treatment of arthritis and other inflammatory conditions based on results from the ORAL ...
T. Kragstrup   +6 more
semanticscholar   +1 more source

Miłosz: Self-Reflection as the Topic of a Poetic Description [PDF]

open access: yes, 2016
Czesław Miłosz’s poetry displays two reverberating topics which may be defined as contradictory existence and world experiences. One of those is the admiration for the beauty of the world and awe consequent upon capturing the simultaneous existence of ...
Stelmaszczyk, Barbara
core   +2 more sources

Use of the JAK Inhibitor Ruxolitinib in the Treatment of Hemophagocytic Lymphohistiocytosis

open access: yesFrontiers in Immunology, 2021
Hemophagocytic lymphohistiocytosis (HLH) is a rare hyperinflammatory syndrome driven by overactive T cells and macrophages that abundantly secrete numerous pro-inflammatory cytokines, including interferon (IFN)-gamma, interleukin (IL)-1-beta, IL-2, IL-6,
Camille Keenan   +2 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy