Results 241 to 250 of about 314,954 (325)

Outcomes of Nivolumab Plus Ipilimumab After Atezolizumab Plus Bevacizumab in Advanced HCC: An International Multicentre Study

open access: yesLiver International, Volume 46, Issue 2, February 2026.
ABSTRACT Background/Aims Immune checkpoint inhibitors (ICIs) have transformed advanced HCC treatment. The benefit of sequential immunotherapy after prior ICI failure remains unclear. Given the expanded use of atezolizumab plus bevacizumab (Ate/Bev) over the past 5 years, we explored the real‐world outcomes of nivolumab plus ipilimumab (Nivo/Ipi) in ...
Jung Sun Kim   +15 more
wiley   +1 more source

Principles for Optimal Drug Selection in IgA Nephropathy—Time for Integrating Pathogenesis and Clinical Markers to Guide Therapy

open access: yesNephrology, Volume 31, Issue 2, February 2026.
ABSTRACT IgA nephropathy is a progressive glomerular disease with a variable clinical course and a substantial risk of progression to end‐stage kidney failure. While proteinuria has long been the central therapeutic target, insights into disease pathogenesis indicate that haematuria should also guide treatment decisions. Based on the pathophysiology of
Yusuke Suzuki
wiley   +1 more source

Orexin Receptor Antagonism Improves Sleep Quality and Mitigates Lipopolysaccharide‐Induced Inflammatory Responses in a Mouse Model

open access: yesThe FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Inhibiting orexin improves sleep quality and mitigates inflammation of LPS‐induced mice. ABSTRACT Alterations in the immune system, stemming from sleep/wakefulness disorders, increase the risk of inflammatory pathologies. Orexin, a hypothalamic neuropeptide, regulates sleep and wakefulness.
Dai Horiuchi   +7 more
wiley   +1 more source

Diagnosis of a Perforated Small Bowel Diverticulum in an Elderly Patient Hindered by a Nuck Cyst: A Case Report. [PDF]

open access: yesCureus
Leal Isla Flores V   +4 more
europepmc   +1 more source

From the heart to the kidney: A case report of Wunderlich syndrome following structural valve intervention. [PDF]

open access: yesRadiol Case Rep
Coutinho HMR   +8 more
europepmc   +1 more source

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