Results 131 to 140 of about 2,795,897 (305)

ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells

open access: yesAdvanced Science, EarlyView.
With a powerful combination of in vivo, ex vivo, and in vitro models, the authors highlight a novel FGF‐ERK signaling regulation of YAP at the S128 site in neural crest‐derived stem cells. This study opens exciting new directions in stem cell biology and craniofacial biology, paving the way for potential innovations in the treatment of craniofacial ...
Xiaolei Zhao   +16 more
wiley   +1 more source

James C. Furman from James P. Boyce

open access: yes
A four page letter from James P.
Boyce, James P.
core  

Letter from James D. Porter, former Governor of Tennessee, Paris, Tennessee, to James Bowron, South Pittsburg, Tennessee, May 3, 1880

open access: yes, 1880
This is an item from the James Bowron Papers, a collection of papers and materials relating to James Bowron, one of the 19th century iron and mining pioneers in the ...
Porter, James D. (James Davis), 1828-1912
core  

Reverend James M. Chiles to James C. Furman

open access: yes
A two page letter and envelope from Reverend James M.
Chiles, James M.
core   +1 more source

Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer

open access: yesAdvanced Science, EarlyView.
We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel   +16 more
wiley   +1 more source

James W. Terrell to James R. Thomas, December 8, 1888

open access: yes, 2018
In this letter of December 8, 1888, James W. Terrell writes to Jim (James R. Thomas) instructing him to bid on a piece of property in Swain County. Terrell speculates the Cathcart land is endangered in Swain County and he has already secured most of the ...
Terrell, James W., 1829-1908;
core  

Heme‐NO Dilates Arteries via Mobilization of NO Moieties From an Intracellular NO Store Within Vascular Smooth Muscle Cells

open access: yesAdvanced Science, EarlyView.
Nitrosyl heme emerges as an extracellular nitrodilator that dilates arteries without crossing the cell membrane. Instead, heme‐NO mobilizes NO moieties from a preformed intracellular NO store within vascular smooth muscle, providing both functional and chemical evidence for the NANOS model, revealing a previously unrecognized mechanism of arterial ...
Taiming Liu   +9 more
wiley   +1 more source

James E. Tyler to James C. Furman

open access: yes
A three page letter and envelope from James E.
Tyler, James E.
core  

Letter from C. E. James, Pig and Bar Iron, Chattanooga, Tennessee, to James Bowron, Pittsburg, Tennessee, April 28, 1880

open access: yes, 1880
This is an item from the James Bowron Papers, a collection of papers and materials relating to James Bowron, one of the 19th century iron and mining pioneers in the ...
James, C. E.
core  

Home - About - Disclaimer - Privacy