Results 181 to 190 of about 3,588,451 (257)

Robots and Minimal, Physics‐Informed Features: A Hybrid Framework for Enzyme Catalysis

Advanced Science, EarlyView.
Robotic experimentation and physics‐informed machine learning combine to predict enzyme substrate scope. With a handful of interpretable features derived from docking and quantum mechanics calculations, our model rivals descriptor‐heavy AI approaches and extrapolates to unseen substrates and enzyme classes.
Natalia Onishchenko, Eric S. Larsen, Govind Paneru, Kisung Lee, Diana V. Kolygina, Yankai Jia, Elizabeth Maria Clarissa, Wai‐Shing Wong, Bartosz A. Grzybowski   +8 more
wiley   +1 more source

Born This Way: Individuality Is Seeded Before Birth and Robust to Ecological Stress. [PDF]

Ecol Lett
Gallagher JH, Perkes AD, Chang CC, Chirila ES, Kacevas K, Laskowski KL.   +5 more
europepmc   +1 more source

Space Jam‐Ming: Generating Interstitial Space Using Fragmented Granular GelMA to Investigate Novel Paradigms of Cancer Metastasis

Advanced Science, EarlyView.
Microgels enable independent control of stiffness and interstitial space, overcoming limitations of conventional 3D hydrogels. Using fragmented gelatin methacryloyl microgels, we show that stiffness does not restrict non‐metastatic breast cancer growth, contrary to bulk hydrogels, and reveal the role of adherent‐to‐suspension transition in cancer ...
Danielle Vahala, Zhuang Min Lee, Sebastian E. Amos, Dong Woo Son, Jong Hwa Byun, Farzan Navaeipour, Jiayue Li, Kai L. Metzner, Ji Hoon Jeong, Juyeon Kim, Yongsung Hwang, Brendan F. Kennedy, Khoon S. Lim, Hee Seung Lee, Hyun Woo Park, Yu Suk Choi   +15 more
wiley   +1 more source

Correction: From lab to ocean: bridging swimming energetics and wild movements to understand red drum (Sciaenops ocellatus) behavior in a tidal estuary. [PDF]

J Exp Biol
Gibbs BJ, Strother JA, Morgan CR, Pinton D, Canestrelli A, Liao JC.   +5 more
europepmc   +1 more source

Carbohydrate‐Mediated Cellular Uptake of Boronic Acid Hybrids In Cellulo and Insulin‐Deficient Zebrafish: Live Imaging and Application of Multiphoton FLIM

Advanced Science, EarlyView.
Boronic acid‐based fluorescent hybrids have been used as part of a versatile platform for real‐time metabolic bioimaging across cellular and organismal scales. Including glucose‐responsive imaging in living cells and in an insulin‐deficient vertebrate model, this work opens new opportunities for the development of precision diagnostics, metabolic ...
Haobo Ge, John S. Fossey, David Gonzalez Calatayud, Stephen E. Flower, Sabrina Wang, Hanna Aitessaid, Melita Tvardauskaite, Julia Dudzic, Max Jewell, Charareh Pourzand, Stanley W. Botchway, David Gurevich, Tony D. James, Sofia I. Pascu   +13 more
wiley   +1 more source

Correction to: Information from social ties predicts conspiracy beliefs: Evidence from the attempted assassination of Donald Trump. [PDF]

PNAS Nexus
europepmc   +1 more source

Health Care Utilization and Costs Associated With Blue-Light vs White-Light Cystoscopy: A Real-World Bladder Cancer Population. [PDF]

JU Open Plus
Tyson MD, Choudry MM, McKee C, Kalaria S, James C, Engel-Nitz NM, Johnson MG, Barnes TL.   +7 more
europepmc   +1 more source

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss

Advanced Science, EarlyView.
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale, Barbara Vona, Richard J. Goodyear, Richard T. Osgood, Jun Shen, Sami S. Amr, Karen Mojica, Michaela A. H. Hofrichter, Jörg Schröder, Sophie Flandin, Paul Gratias, Ricardo Vera‐Monroy, Katherine Callahan, Kerry L. Gudlewski, Rolen Quadros, Masato Ohtsuka, JoAnn McGee, Edward J. Walsh, Cynthia C. Morton, Thomas Haaf, Channabasavaiah Gurumurthy, James E. Saunders, Guy P. Richardson, Artur A. Indzhykulian   +23 more
wiley   +1 more source

Editorial: The Path in Psoriatic Disease-From Conceptual Clarity to Clinical Translation. [PDF]

Int J Rheum Dis
Huo AP, Cheng TK, Wei JC.
europepmc   +1 more source

Multifunctional Quantum Sensing Using Single Spins in a van der Waals Crystal

Advanced Science, EarlyView.
The work demonstrates a dual quantum sensing of temperature and magnetic field using spin‐complex quantum emitters in hexagonal boron nitride (hBN). Temperature sensing via zero‐phonon‐line shifts and magnetometry via optically detected magnetic resonances, enable simultaneous local thermometry and magnetic‐field measurements.
James Liddle‐Wesolowski, Konosuke Shimazaki, Jiyun Kim, Benjamin Whitefield, Kenji Watanabe, Takashi Taniguchi, Mehran Kianinia, Igor Aharonovich   +7 more
wiley   +1 more source